Treatment of enteric fever with pefloxacin for 7 days versus 5 days: A randomized clinical trial

Serhat Ünal; Murat Hayran; Serdar Tuncer; Deniz Gür; Ömrüm Uzun; Murat Akova; H. Erdal Akalin

doi:10.1128/aac.40.12.2898

Treatment of enteric fever with pefloxacin for 7 days versus 5 days: A randomized clinical trial

Serhat Ünal
, Murat Hayran
, Serdar Tuncer
, Deniz Gür
, Ömrüm Uzun
, Murat Akova
, H. Erdal Akalin

Araştırma sonucu: Dergiye katkı › Makale › bilirkişi

13 Alıntılar (Scopus)

Özet

In this prospective study of enteric fever, 22 patients received 400 mg of pefloxacin twice daily for 5 days (group A) and 24 received 400 mg of pefloxacin twice daily for 7 days (group B). Causative microorganisms were Salmonella typhi (8 in group A, 11 in group B) and Salmonella paratyphi B (14 in group A, 13 in group B). The clinical cure and bacterial eradication rates were 96% (21 of 22) in group A and 100% in group B. In conclusion, 5-day oral administration of pefloxacin was as effective as 7-day treatment of enteric fever caused by Salmonella spp.

Orijinal dil	İngilizce
Sayfa (başlangıç-bitiş)	2898-2900
Sayfa sayısı	3
Dergi	Antimicrobial Agents and Chemotherapy
Hacim	40
Basın numarası	12
DOI'lar	https://doi.org/10.1128/aac.40.12.2898
Yayın durumu	Yayınlandı - Ara 1996
Harici olarak yayınlandı	Evet

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10.1128/aac.40.12.2898

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title = "Treatment of enteric fever with pefloxacin for 7 days versus 5 days: A randomized clinical trial",

abstract = "In this prospective study of enteric fever, 22 patients received 400 mg of pefloxacin twice daily for 5 days (group A) and 24 received 400 mg of pefloxacin twice daily for 7 days (group B). Causative microorganisms were Salmonella typhi (8 in group A, 11 in group B) and Salmonella paratyphi B (14 in group A, 13 in group B). The clinical cure and bacterial eradication rates were 96\% (21 of 22) in group A and 100\% in group B. In conclusion, 5-day oral administration of pefloxacin was as effective as 7-day treatment of enteric fever caused by Salmonella spp.",

author = "Serhat {\"U}nal and Murat Hayran and Serdar Tuncer and Deniz G{\"u}r and {\"O}mr{\"u}m Uzun and Murat Akova and \{Erdal Akalin\}, H.",

year = "1996",

month = dec,

doi = "10.1128/aac.40.12.2898",

language = "English",

volume = "40",

pages = "2898--2900",

journal = "Antimicrobial Agents and Chemotherapy",

issn = "0066-4804",

publisher = "American Society for Microbiology",

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}

TY - JOUR

T1 - Treatment of enteric fever with pefloxacin for 7 days versus 5 days

T2 - A randomized clinical trial

AU - Ünal, Serhat

AU - Hayran, Murat

AU - Tuncer, Serdar

AU - Gür, Deniz

AU - Uzun, Ömrüm

AU - Akova, Murat

AU - Erdal Akalin, H.

PY - 1996/12

Y1 - 1996/12

N2 - In this prospective study of enteric fever, 22 patients received 400 mg of pefloxacin twice daily for 5 days (group A) and 24 received 400 mg of pefloxacin twice daily for 7 days (group B). Causative microorganisms were Salmonella typhi (8 in group A, 11 in group B) and Salmonella paratyphi B (14 in group A, 13 in group B). The clinical cure and bacterial eradication rates were 96% (21 of 22) in group A and 100% in group B. In conclusion, 5-day oral administration of pefloxacin was as effective as 7-day treatment of enteric fever caused by Salmonella spp.

AB - In this prospective study of enteric fever, 22 patients received 400 mg of pefloxacin twice daily for 5 days (group A) and 24 received 400 mg of pefloxacin twice daily for 7 days (group B). Causative microorganisms were Salmonella typhi (8 in group A, 11 in group B) and Salmonella paratyphi B (14 in group A, 13 in group B). The clinical cure and bacterial eradication rates were 96% (21 of 22) in group A and 100% in group B. In conclusion, 5-day oral administration of pefloxacin was as effective as 7-day treatment of enteric fever caused by Salmonella spp.

UR - https://www.scopus.com/pages/publications/0029828260

U2 - 10.1128/aac.40.12.2898

DO - 10.1128/aac.40.12.2898

M3 - Article

C2 - 9124864

AN - SCOPUS:0029828260

SN - 0066-4804

VL - 40

SP - 2898

EP - 2900

JO - Antimicrobial Agents and Chemotherapy

JF - Antimicrobial Agents and Chemotherapy

IS - 12

ER -

Treatment of enteric fever with pefloxacin for 7 days versus 5 days: A randomized clinical trial

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