TY - JOUR
T1 - Theranostic advances and the role of molecular imprinting in disease management
AU - Yilmaz, Eylul Gulsen
AU - Küçük, Beyza Nur
AU - Aslan, Yusuf
AU - Erdem, Özgecan
AU - Saylan, Yeşeren
AU - Inci, Fatih
AU - Denizli, Adil
N1 - Publisher Copyright:
© 2025 The Author(s)
PY - 2025/4/18
Y1 - 2025/4/18
N2 - Molecular imprinting has become an effective technology in the realm of diagnosing diseases, providing unparalleled specificity and sensitivity. This method is a promising trend in current medical research. This review examines the utilization of molecularly imprinted polymers (MIPs) in theranostic that integrates diagnostic functionalities for personalized medicine. The present work briefly discusses the fundamental concepts of molecular imprinting and how it has evolved into a versatile platform. Subsequently, the utilization of MIPs in the advancement of biosensors is focused, specifically emphasizing their contribution to the detection and diagnosis of diseases. The therapeutic potential of MIPs, focusing on targeted drug delivery and controlled release systems and the integration of MIPs into theranostic platforms is explored through case studies, showcasing the technology's ability to simultaneously diagnose and treat diseases. Finally, we address the current challenges facing MIPs and discuss future perspectives, emphasizing the potential of this technology to revolutionize the next generation.
AB - Molecular imprinting has become an effective technology in the realm of diagnosing diseases, providing unparalleled specificity and sensitivity. This method is a promising trend in current medical research. This review examines the utilization of molecularly imprinted polymers (MIPs) in theranostic that integrates diagnostic functionalities for personalized medicine. The present work briefly discusses the fundamental concepts of molecular imprinting and how it has evolved into a versatile platform. Subsequently, the utilization of MIPs in the advancement of biosensors is focused, specifically emphasizing their contribution to the detection and diagnosis of diseases. The therapeutic potential of MIPs, focusing on targeted drug delivery and controlled release systems and the integration of MIPs into theranostic platforms is explored through case studies, showcasing the technology's ability to simultaneously diagnose and treat diseases. Finally, we address the current challenges facing MIPs and discuss future perspectives, emphasizing the potential of this technology to revolutionize the next generation.
KW - Diagnostics
KW - Molecular imprinted technique
KW - Sensor
KW - Therapeutics
UR - https://www.scopus.com/pages/publications/105000949321
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=performanshacettepe&SrcAuth=WosAPI&KeyUT=WOS:001457107900001&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.1016/j.isci.2025.112186
DO - 10.1016/j.isci.2025.112186
M3 - Review article
C2 - 40224001
AN - SCOPUS:105000949321
SN - 2589-0042
VL - 28
SP - 112186
JO - iScience
JF - iScience
IS - 4
M1 - 112186
ER -