TY - JOUR
T1 - The UniProtKB guide to the human proteome
AU - The UniProt Consortium
AU - Breuza, Lionel
AU - Poux, Sylvain
AU - Estreicher, Anne
AU - Famiglietti, Maria Livia
AU - Magrane, Michele
AU - Tognolli, Michael
AU - Bridge, Alan
AU - Baratin, Delphine
AU - Redaschi, Nicole
AU - Xenarios, Ioannis
AU - Bougueleret, Lydie
AU - Bairoch, Amos
AU - Aimo, Lucila
AU - Auchincloss, Andrea
AU - Axelsen, Kristian
AU - Argoud-Puy, Ghislaine
AU - Bansal, Parit
AU - Binz, Pierre Alain
AU - Blatter, Marie Claude
AU - Boeckmann, Brigitte
AU - Bolleman, Jerven
AU - Boutet, Emmanuel
AU - Braconi-Quintaje, Silvia
AU - Casal-Casas, Cristina
AU - De Castro, Edouard
AU - Cerutti, Lorenzo
AU - Coudert, Elisabeth
AU - Cuche, Beatrice
AU - Cusin, Isabelle
AU - Doche, Mikael
AU - Dornevil, Dolnide
AU - Duvaud, Severine
AU - Ferro-Rojas, Serenella
AU - Feuermann, Marc
AU - Gasteiger, Elisabeth
AU - Gehant, Sebastien
AU - Gerritsen, Vivienne
AU - Gos, Arnaud
AU - Gruaz-Gumowski, Nadine
AU - Hinz, Ursula
AU - Hulo, Chantal
AU - James, Janet
AU - Jimenez, Silvia
AU - Jungo, Florence
AU - Keller, Guillaume
AU - Kerhornou, Arnaud
AU - Kappler, Thomas
AU - Lane, Lydie
AU - Lara, Vicente
AU - Dogan, Tunca
N1 - Publisher Copyright:
© The Author(s) 2016. Published by Oxford University Press.
PY - 2016
Y1 - 2016
N2 - Advances in high-throughput and advanced technologies allow researchers to routinely perform whole genome and proteome analysis. For this purpose, they need high-quality resources providing comprehensive gene and protein sets for their organisms of interest. Using the example of the human proteome, we will describe the content of a complete proteome in the UniProt Knowledgebase (UniProtKB). We will show how manual expert curation of UniProtKB/Swiss-Prot is complemented by expert-driven automatic annotation to build a comprehensive, high-quality and traceable resource. We will also illustrate how the complexity of the human proteome is captured and structured in UniProtKB.
AB - Advances in high-throughput and advanced technologies allow researchers to routinely perform whole genome and proteome analysis. For this purpose, they need high-quality resources providing comprehensive gene and protein sets for their organisms of interest. Using the example of the human proteome, we will describe the content of a complete proteome in the UniProt Knowledgebase (UniProtKB). We will show how manual expert curation of UniProtKB/Swiss-Prot is complemented by expert-driven automatic annotation to build a comprehensive, high-quality and traceable resource. We will also illustrate how the complexity of the human proteome is captured and structured in UniProtKB.
UR - https://www.scopus.com/pages/publications/84971012147
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=performanshacettepe&SrcAuth=WosAPI&KeyUT=WOS:000370928300001&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.1093/database/bav120
DO - 10.1093/database/bav120
M3 - Article
C2 - 26896845
AN - SCOPUS:84971012147
SN - 1758-0463
VL - 2016
JO - Database : the journal of biological databases and curation
JF - Database : the journal of biological databases and curation
ER -