Synthesis and structure of 6-bromo-2-(diethoxy-methyl)-2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate

Firudin I. Guseinov; Aida I. Samigullina; Tuncer Hökelek; Sahil Z. Hamidov; Jamal Lasri; Khudayar I. Hasanov; Tahir A. Javadzade; Alebel N. Belay

doi:10.1107/S2056989025005778

Synthesis and structure of 6-bromo-2-(diethoxy-methyl)-2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate

Firudin I. Guseinov
, Aida I. Samigullina
, Tuncer Hökelek
, Sahil Z. Hamidov
, Jamal Lasri
, Khudayar I. Hasanov
, Tahir A. Javadzade
, Alebel N. Belay

Hacettepe Üniversitesi

Araştırma sonucu: Dergiye katkı › Makale › bilirkişi

Özet

In the title solvated molecular salt, C₁₈H₂₂BrN₂O₃⁺·Cl^- ·CH₃CN, the imidazole ring is in envelope conformation and the pyridine and phenyl rings are oriented at a dihedral angle of 72.52 (5)^°. In the crystal, O—H· · ·Cl and N—H· · ·Cl hydrogen bonds link the cations and anions into centrosymmetric tetramers enclosing R²₄(12) loops. Short Br· · ·Cl [3.2313 (4) A^̊] and O· · ·Cl [3.0490 (10) A^̊] contacts are observed. A Hirshfeld surface analysis of the structure indicates that the most important contributions for the crystal packing are from H· · ·H (52.4%), H· · ·C/C· · ·H (12.1%), H· · ·Br/Br· · ·H (11.0%) and H· · ·Cl/Cl· · ·H (10.2%) interactions.

Orijinal dil	İngilizce
Sayfa (başlangıç-bitiş)	672-675
Sayfa sayısı	4
Dergi	Acta Crystallographica Section E: Crystallographic Communications
Hacim	81
Basın numarası	Pt 8
DOI'lar	https://doi.org/10.1107/S2056989025005778
Yayın durumu	Yayınlandı - 1 Ağu 2025

Belgeye Erişim

10.1107/S2056989025005778

Diger dosyalar ve linkler

Link to publication in Scopus

Bundan alıntı yap

Guseinov, F. I., Samigullina, A. I., Hökelek, T., Hamidov, S. Z., Lasri, J., Hasanov, K. I., Javadzade, T. A., & Belay, A. N. (2025). Synthesis and structure of 6-bromo-2-(diethoxy-methyl)-2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate. Acta Crystallographica Section E: Crystallographic Communications, 81(Pt 8), 672-675. https://doi.org/10.1107/S2056989025005778

@article{732a46c04d814ffc9386ca14b1bbbb75,

title = "Synthesis and structure of 6-bromo-2-(diethoxy-methyl)-2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate",

abstract = "In the title solvated molecular salt, C18H22BrN2O3+·Cl- ·CH3CN, the imidazole ring is in envelope conformation and the pyridine and phenyl rings are oriented at a dihedral angle of 72.52 (5)°. In the crystal, O—H· · ·Cl and N—H· · ·Cl hydrogen bonds link the cations and anions into centrosymmetric tetramers enclosing R24(12) loops. Short Br· · ·Cl [3.2313 (4) Å] and O· · ·Cl [3.0490 (10) Å] contacts are observed. A Hirshfeld surface analysis of the structure indicates that the most important contributions for the crystal packing are from H· · ·H (52.4\%), H· · ·C/C· · ·H (12.1\%), H· · ·Br/Br· · ·H (11.0\%) and H· · ·Cl/Cl· · ·H (10.2\%) interactions.",

keywords = "crystal structure, hydrogen bond, imidazole, non-covalent interactions",

author = "Guseinov, \{Firudin I.\} and Samigullina, \{Aida I.\} and Tuncer H{\"o}kelek and Hamidov, \{Sahil Z.\} and Jamal Lasri and Hasanov, \{Khudayar I.\} and Javadzade, \{Tahir A.\} and Belay, \{Alebel N.\}",

year = "2025",

month = aug,

day = "1",

doi = "10.1107/S2056989025005778",

language = "English",

volume = "81",

pages = "672--675",

journal = "Acta Crystallographica Section E: Crystallographic Communications",

issn = "2056-9890",

publisher = "International Union of Crystallography",

number = "Pt 8",

}

Guseinov, FI, Samigullina, AI, Hökelek, T, Hamidov, SZ, Lasri, J, Hasanov, KI, Javadzade, TA & Belay, AN 2025, 'Synthesis and structure of 6-bromo-2-(diethoxy-methyl)-2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate', Acta Crystallographica Section E: Crystallographic Communications, hac. 81, no. Pt 8, pp. 672-675. https://doi.org/10.1107/S2056989025005778

Synthesis and structure of 6-bromo-2-(diethoxy-methyl)-2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate. / Guseinov, Firudin I.; Samigullina, Aida I.; Hökelek, Tuncer et al.
In: Acta Crystallographica Section E: Crystallographic Communications, Hac. 81, No. Pt 8, 01.08.2025, p. 672-675.

Araştırma sonucu: Dergiye katkı › Makale › bilirkişi

TY - JOUR

T1 - Synthesis and structure of 6-bromo-2-(diethoxy-methyl)-2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate

AU - Guseinov, Firudin I.

AU - Samigullina, Aida I.

AU - Hökelek, Tuncer

AU - Hamidov, Sahil Z.

AU - Lasri, Jamal

AU - Hasanov, Khudayar I.

AU - Javadzade, Tahir A.

AU - Belay, Alebel N.

PY - 2025/8/1

Y1 - 2025/8/1

N2 - In the title solvated molecular salt, C18H22BrN2O3+·Cl- ·CH3CN, the imidazole ring is in envelope conformation and the pyridine and phenyl rings are oriented at a dihedral angle of 72.52 (5)°. In the crystal, O—H· · ·Cl and N—H· · ·Cl hydrogen bonds link the cations and anions into centrosymmetric tetramers enclosing R24(12) loops. Short Br· · ·Cl [3.2313 (4) Å] and O· · ·Cl [3.0490 (10) Å] contacts are observed. A Hirshfeld surface analysis of the structure indicates that the most important contributions for the crystal packing are from H· · ·H (52.4%), H· · ·C/C· · ·H (12.1%), H· · ·Br/Br· · ·H (11.0%) and H· · ·Cl/Cl· · ·H (10.2%) interactions.

AB - In the title solvated molecular salt, C18H22BrN2O3+·Cl- ·CH3CN, the imidazole ring is in envelope conformation and the pyridine and phenyl rings are oriented at a dihedral angle of 72.52 (5)°. In the crystal, O—H· · ·Cl and N—H· · ·Cl hydrogen bonds link the cations and anions into centrosymmetric tetramers enclosing R24(12) loops. Short Br· · ·Cl [3.2313 (4) Å] and O· · ·Cl [3.0490 (10) Å] contacts are observed. A Hirshfeld surface analysis of the structure indicates that the most important contributions for the crystal packing are from H· · ·H (52.4%), H· · ·C/C· · ·H (12.1%), H· · ·Br/Br· · ·H (11.0%) and H· · ·Cl/Cl· · ·H (10.2%) interactions.

KW - crystal structure

KW - hydrogen bond

KW - imidazole

KW - non-covalent interactions

UR - https://www.scopus.com/pages/publications/105012841302

U2 - 10.1107/S2056989025005778

DO - 10.1107/S2056989025005778

M3 - Article

C2 - 40777527

AN - SCOPUS:105012841302

SN - 2056-9890

VL - 81

SP - 672

EP - 675

JO - Acta Crystallographica Section E: Crystallographic Communications

JF - Acta Crystallographica Section E: Crystallographic Communications

IS - Pt 8

ER -

Synthesis and structure of 6-bromo-2-(diethoxy-methyl)-2-hydroxy-3-phenyl-2,3-dihydro-1Himidazo[1,2-a]pyridin-4-ium chloride acetonitrile monosolvate

Özet

Belgeye Erişim

Diger dosyalar ve linkler

Parmak izi

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