Phenolic compounds from Globularia cordifolia

From the methanolic extract of the underground parts of Globularia cordifolia, a new neolignan diglycoside, dehydrodiconiferyl alcohol 9-O-βD-glucopyranosyl-(1→2)-β-D-glucopyranoside (1) was isolated along with a known neolignan glycoside, dehydrodiconiferyl alcohol 9-O-β-D-glucopyranoside (2). In addition, 2 flavone glycosides, chrysoeriol 7-O-β-D-allopyranosyl-(1→2)-β-D-glucopyranoside (3), stachyspinoside (4) and 5 phenylethanoid glycosides, verbascoside (5), isoverbascoside (6), leucosceptoside A (7), martynoside (8) and rossicaside A (9) were obtained and characterized. The structures of the isolates were established by ID and 2D NMR spectroscopy in combination with IR, UV and MS analysis.