New thiazolo[3,2-a] pyrimidine derivatives, synthesis and calcium antagonistic activities

The synthesis of a series of thiazolo[3,2-a]pyrimidine derivatives were described. The structures of the compounds were elucidated by IR, ¹H-NMR, ¹³C and elementary analysis. The compounds were evaluated for their calcium antagonistic activities using nifedipine as standart compound. All of the compounds were found to be less potent than nifedipine.