Multidisciplinary Tumor Board Evaluation of Pediatric Patients with Adrenocortical Tumors Across Seven International Centers

Currently, there are no international guidelines for diagnosing and treating pediatric adrenocortical carcinoma (ACC). This study examines how treatment recommendations vary across specialized centers in different countries. It is the first case-based analysis of an international agreement on pediatric ACC management. The findings reveal significant differences in treatment approaches between centers, even though individual tumor boards within each institution show strong internal consensus. These discrepancies highlight the need for global collaboration and standardized guidelines, particularly for rare cancers. Enhancing case-based discussions between institutions could help unify treatment strategies and improve care for pediatric patients with ACC.