Antigenic analysis of wild-type measles viruses currently isolated in Turkey

Gülay Korukluoǧlu; Pinar Zarakolu

Antigenic analysis of wild-type measles viruses currently isolated in Turkey

Gülay Korukluoǧlu
, Pinar Zarakolu

Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı

Refik Saydam Hygiene Center

Araştırma sonucu: Dergiye katkı › Makale › bilirkişi

2 Alıntılar (Scopus)

Özet

The aim of this study was to determine the genetic and antigenic diversity of vaccine-type and wild-type measles viruses by using different antisera in a neutralization assay. Virus strains included genotype A, D3 and D6 clades, and five different groups of antibodies were used. Wild-type measles viruses isolated in Turkey have been classified as D6 and the others isolated in Japan as D3. Antisera used in the assay were against genotype A, D3 and D6. Regardless of the antigenic diversity, protective antibody level (≥1/16) was determined against different genotypes of measles virus.

Orijinal dil	İngilizce
Sayfa (başlangıç-bitiş)	105-108
Sayfa sayısı	4
Dergi	Turkish Journal of Pediatrics
Hacim	48
Basın numarası	2
Yayın durumu	Yayınlandı - 2006

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abstract = "The aim of this study was to determine the genetic and antigenic diversity of vaccine-type and wild-type measles viruses by using different antisera in a neutralization assay. Virus strains included genotype A, D3 and D6 clades, and five different groups of antibodies were used. Wild-type measles viruses isolated in Turkey have been classified as D6 and the others isolated in Japan as D3. Antisera used in the assay were against genotype A, D3 and D6. Regardless of the antigenic diversity, protective antibody level (≥1/16) was determined against different genotypes of measles virus.",

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year = "2006",

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AU - Korukluoǧlu, Gülay

AU - Zarakolu, Pinar

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AB - The aim of this study was to determine the genetic and antigenic diversity of vaccine-type and wild-type measles viruses by using different antisera in a neutralization assay. Virus strains included genotype A, D3 and D6 clades, and five different groups of antibodies were used. Wild-type measles viruses isolated in Turkey have been classified as D6 and the others isolated in Japan as D3. Antisera used in the assay were against genotype A, D3 and D6. Regardless of the antigenic diversity, protective antibody level (≥1/16) was determined against different genotypes of measles virus.

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KW - Measles virus

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JO - Turkish Journal of Pediatrics

JF - Turkish Journal of Pediatrics

IS - 2

ER -

Antigenic analysis of wild-type measles viruses currently isolated in Turkey

Özet

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