TY - CHAP
T1 - Trace Element Containing Nano-HAp for Preventing Musculoskeletal Infections
AU - Gizer, Merve
AU - Boyacıoğlu, Özge
AU - Korkusuz, Petek
AU - Korkusuz, Feza
N1 - Publisher Copyright:
© 2021, The Author(s), under exclusive license to Springer Nature Switzerland AG.
PY - 2021
Y1 - 2021
N2 - Musculoskeletal infections are difficult to diagnose and rapidly reach the chronic phase that is difficult to treat. Osteomyelitis and septic arthritis are inflammatory musculoskeletal diseases and their recovery should contain bone or joint regeneration approaches. Nanometer-sized hydroxyapatite is the main inorganic component of the bone tissue that resembles its extracellular matrix. Nanometer-sized hydroxyapatite composite is also an efficient carrier for various regenerative molecules and medicine. Trace elements on the other hand enhance bone formation, mineralization and have antibacterial properties. Bioactivity, biocompatibility, and antibacterial properties of nanometer-sized hydroxyapatite can be gained and improved with trace elements such as zinc, boron, magnesium, strontium, and molybdenum. This chapter summarizes studies on the effects of zinc, boron, magnesium, strontium, and/or molybdenum-doped nanometer-sized hydroxyapatite that can be used to treat musculoskeletal infections.
AB - Musculoskeletal infections are difficult to diagnose and rapidly reach the chronic phase that is difficult to treat. Osteomyelitis and septic arthritis are inflammatory musculoskeletal diseases and their recovery should contain bone or joint regeneration approaches. Nanometer-sized hydroxyapatite is the main inorganic component of the bone tissue that resembles its extracellular matrix. Nanometer-sized hydroxyapatite composite is also an efficient carrier for various regenerative molecules and medicine. Trace elements on the other hand enhance bone formation, mineralization and have antibacterial properties. Bioactivity, biocompatibility, and antibacterial properties of nanometer-sized hydroxyapatite can be gained and improved with trace elements such as zinc, boron, magnesium, strontium, and molybdenum. This chapter summarizes studies on the effects of zinc, boron, magnesium, strontium, and/or molybdenum-doped nanometer-sized hydroxyapatite that can be used to treat musculoskeletal infections.
KW - Hydroxyapatite
KW - Musculoskeletal infections
KW - Osteomyelitis
KW - Septic arthritis
KW - Trace elements
UR - https://www.scopus.com/pages/publications/85105617015
U2 - 10.1007/978-3-030-64410-9_14
DO - 10.1007/978-3-030-64410-9_14
M3 - Chapter
AN - SCOPUS:85105617015
T3 - Nanotechnology in the Life Sciences
SP - 269
EP - 289
BT - Nanotechnology in the Life Sciences
PB - Springer Science and Business Media B.V.
ER -