Three pediatric cases of accidental levetiracetam overdose administration for long term

Levetiracetam therapy in infancy and childhood epilepsies has become more preffered due to being an effective and well tolerated. There are many articles about levetiracetam side effects. But, up to this time, few datas were reported about the side effects due to accidentally long term use of levetiracetam with the doses higher than recommended in childhood. We evaluated three pediatric cases diagnosed with epilepsy given accidentally high-dose levetiracetam in this article. Patients were administered accidentally 87 mg/kg/d, 100 mg/kg/d and 166 mg/kg/d doses of levetiracetam oral form for one to three months. Suprisingly, no side effects were observed with these high doses of use.