Teriflunomide-Induced Palmoplantar Pustular Psoriasis: Case Report and Review of the Literature

Ezgi Demirel Ozbek; Neslihan Akdogan; Deniz Ates Ozdemir; Nazire Pinar Acar Ozen; Asli Tuncer

doi:10.7759/cureus.42845

Teriflunomide-Induced Palmoplantar Pustular Psoriasis: Case Report and Review of the Literature

Ezgi Demirel Ozbek
, Neslihan Akdogan
, Deniz Ates Ozdemir
, Nazire Pinar Acar Ozen
, Asli Tuncer

Hacettepe University

Research output: Contribution to journal › Review article › peer-review

Abstract

Teriflunomide is a once-daily oral immunomodulatory disease-modifying treatment for multiple sclerosis (MS). Skin reactions are an infrequent side effect of teriflunomide. Here, we present the case of a 52-year-old female patient with ankylosing spondylitis who was consulted for demyelinating lesions and limb weakness. She was diagnosed with multiple sclerosis and started treatment with teriflunomide. Palmoplantar pustular psoriasis developed after three weeks of treatment initiation. It is a rare side effect related to teriflunomide.

Original language	English
Number of pages	4
Journal	CUREUS JOURNAL OF MEDICAL SCIENCE
Volume	15
Issue number	8
DOIs	https://doi.org/10.7759/cureus.42845
Publication status	Published - 2 Aug 2023

Keywords

Adverse effects
Immunomodulatory
Multiple sclerosis
Palmoplantar pustular psoriasis
Teriflunamide
Treatments

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10.7759/cureus.42845

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abstract = "Teriflunomide is a once-daily oral immunomodulatory disease-modifying treatment for multiple sclerosis (MS). Skin reactions are an infrequent side effect of teriflunomide. Here, we present the case of a 52-year-old female patient with ankylosing spondylitis who was consulted for demyelinating lesions and limb weakness. She was diagnosed with multiple sclerosis and started treatment with teriflunomide. Palmoplantar pustular psoriasis developed after three weeks of treatment initiation. It is a rare side effect related to teriflunomide.",

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AU - Ozdemir, Deniz Ates

AU - Ozen, Nazire Pinar Acar

AU - Tuncer, Asli

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Teriflunomide-Induced Palmoplantar Pustular Psoriasis: Case Report and Review of the Literature

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Keywords

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