Selective removal of 17β-estradiol with molecularly imprinted particle-embedded cryogel systems

Ilker Koç; Gözde Baydemir; Engin Bayram; Handan Yavuz; Adil Denizli

doi:10.1016/j.jhazmat.2011.07.017

Selective removal of 17β-estradiol with molecularly imprinted particle-embedded cryogel systems

Ilker Koç
, Gözde Baydemir
, Engin Bayram
, Handan Yavuz
, Adil Denizli

Division of Biochemistry

Hacettepe University

Research output: Contribution to journal › Article › peer-review

73 Citations (Scopus)

Abstract

The selective removal of 17β-estradiol (E2) was investigated by using molecularly E2 imprinted (MIP) particle embedded poly(hydroxyethyl methacrylate) (PHEMA) cryogel. PHEMA/MIP composite cryogel was characterized by FTIR, SEM, swelling studies, and surface area measurements. E2 adsorption studies were performed by using aqueous solutions which contain various amounts of E2. The specificity of PHEMA/MIP cryogel to recognition of E2 was performed by using cholesterol and stigmasterol. PHEMA/MIP cryogel exhibited a high binding capacity (5.32mg/gpolymer) and high selectivity for E2 in the presence of competitive molecules, cholesterol (k _{E2/cholesterol}=7.6) and stigmasterol (k _{E2/Stigmasterol}=85.8). There is no significant decrease in adsorption capacity after several adsorption-desorption cycles.

Original language	English
Pages (from-to)	1819-1826
Number of pages	8
Journal	Journal of Hazardous Materials
Volume	192
Issue number	3
DOIs	https://doi.org/10.1016/j.jhazmat.2011.07.017
Publication status	Published - 15 Sept 2011

Keywords

17β-Estradiol
Cryogels
Molecular imprinting (MIP)

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10.1016/j.jhazmat.2011.07.017

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title = "Selective removal of 17β-estradiol with molecularly imprinted particle-embedded cryogel systems",

abstract = "The selective removal of 17β-estradiol (E2) was investigated by using molecularly E2 imprinted (MIP) particle embedded poly(hydroxyethyl methacrylate) (PHEMA) cryogel. PHEMA/MIP composite cryogel was characterized by FTIR, SEM, swelling studies, and surface area measurements. E2 adsorption studies were performed by using aqueous solutions which contain various amounts of E2. The specificity of PHEMA/MIP cryogel to recognition of E2 was performed by using cholesterol and stigmasterol. PHEMA/MIP cryogel exhibited a high binding capacity (5.32mg/gpolymer) and high selectivity for E2 in the presence of competitive molecules, cholesterol (k E2/cholesterol=7.6) and stigmasterol (k E2/Stigmasterol=85.8). There is no significant decrease in adsorption capacity after several adsorption-desorption cycles.",

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author = "Ilker Ko{\c c} and G{\"o}zde Baydemir and Engin Bayram and Handan Yavuz and Adil Denizli",

year = "2011",

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doi = "10.1016/j.jhazmat.2011.07.017",

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T1 - Selective removal of 17β-estradiol with molecularly imprinted particle-embedded cryogel systems

AU - Koç, Ilker

AU - Baydemir, Gözde

AU - Bayram, Engin

AU - Yavuz, Handan

AU - Denizli, Adil

PY - 2011/9/15

Y1 - 2011/9/15

N2 - The selective removal of 17β-estradiol (E2) was investigated by using molecularly E2 imprinted (MIP) particle embedded poly(hydroxyethyl methacrylate) (PHEMA) cryogel. PHEMA/MIP composite cryogel was characterized by FTIR, SEM, swelling studies, and surface area measurements. E2 adsorption studies were performed by using aqueous solutions which contain various amounts of E2. The specificity of PHEMA/MIP cryogel to recognition of E2 was performed by using cholesterol and stigmasterol. PHEMA/MIP cryogel exhibited a high binding capacity (5.32mg/gpolymer) and high selectivity for E2 in the presence of competitive molecules, cholesterol (k E2/cholesterol=7.6) and stigmasterol (k E2/Stigmasterol=85.8). There is no significant decrease in adsorption capacity after several adsorption-desorption cycles.

AB - The selective removal of 17β-estradiol (E2) was investigated by using molecularly E2 imprinted (MIP) particle embedded poly(hydroxyethyl methacrylate) (PHEMA) cryogel. PHEMA/MIP composite cryogel was characterized by FTIR, SEM, swelling studies, and surface area measurements. E2 adsorption studies were performed by using aqueous solutions which contain various amounts of E2. The specificity of PHEMA/MIP cryogel to recognition of E2 was performed by using cholesterol and stigmasterol. PHEMA/MIP cryogel exhibited a high binding capacity (5.32mg/gpolymer) and high selectivity for E2 in the presence of competitive molecules, cholesterol (k E2/cholesterol=7.6) and stigmasterol (k E2/Stigmasterol=85.8). There is no significant decrease in adsorption capacity after several adsorption-desorption cycles.

KW - 17β-Estradiol

KW - Cryogels

KW - Molecular imprinting (MIP)

UR - https://www.scopus.com/pages/publications/80052032504

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DO - 10.1016/j.jhazmat.2011.07.017

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AN - SCOPUS:80052032504

SN - 0304-3894

VL - 192

SP - 1819

EP - 1826

JO - Journal of Hazardous Materials

JF - Journal of Hazardous Materials

IS - 3

ER -

Selective removal of 17β-estradiol with molecularly imprinted particle-embedded cryogel systems

Abstract

Keywords

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