Pulmonary aspergillosis after treatment with infliximab in Still's disease and a literature review of Still's disease and pulmonary aspergillosis

The use of anti-tumor necrosis factor alpha (anti-TNF-alpha) agents has increased during the past decade in rheumatology practice. Opportunistic infections have been reported with anti-TNF-alpha agents in clinical trials and post-marketing usage. Aspergillus infection is a rare opportunistic infection that is associated with immunosuppression, and there are reported cases of pulmonary aspergillosis in various rheumatic diseases treated with anti-TNF-alpha agents. Here, we present the first case of pulmonary aspergillosis associated with infliximab treatment in a patient with Still's disease.