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Proliferating cell nuclear antigen immunoreactivity and the presence of P53 mutation in basaloid squamous cell carcinoma of the larynx

  • GOP
  • Gazi University

Research output: Contribution to journalArticlepeer-review

14 Citations (Scopus)

Abstract

Basaloid squamous cell carcinoma (BSCC) is an aggressive variant of squamous cell carcinoma (SCC) that was first described in 1986. In the English literature, only 28 cases of this histopathological entity have been reported in the larynx. Proliferative features of this infrequent tumor were investigated by proliferating cell nuclear antigen immunoreactivity, and the presence of P53 mutation was also investigated in a series of 4 cases. BSCC was found to share similar features with regular SCC in terms of its proliferation rate and P53 mutation positivity, as well as biological behavior and clinical outcome.

Original languageEnglish
Pages (from-to)382-383
Number of pages2
JournalOncology (Switzerland)
Volume55
Issue number5
DOIs
Publication statusPublished - 1998

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Oncogenes
  • Proliferation markers
  • Squamous cell carcinoma variants

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