Pharmacogenetic testing in psychiatry: Perspective on clinical utility

Frances Adiukwu; Olufisayo Adesokun; Emmanuel Essien; Nadir Yalcin; Ramdas Ransing; Sachin Nagendrappa; Chonnakarn Jatchavala; Ayotunde Bolatito Olakunke; Faisal A. Nawaz; Nagina Khan

doi:10.1016/j.ajp.2023.103674

Pharmacogenetic testing in psychiatry: Perspective on clinical utility

Frances Adiukwu
, Olufisayo Adesokun
, Emmanuel Essien
, Nadir Yalcin
, Ramdas Ransing
, Sachin Nagendrappa
, Chonnakarn Jatchavala
, Ayotunde Bolatito Olakunke
, Faisal A. Nawaz
, Nagina Khan

Division of Clinical Pharmacy

University of Port Harcourt
University of Calabar
Ministry of Health and Family Welfare
St. John's National Academy of Health Sciences
Prince of Songkla University
University of Ilorin
Al Amal Psychiatric Hospital
University of Oxford

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

Pharmacogenetic studies the influence of inherited characteristics on medication. While different from pharmacogenomics, which is a study of the entire genome in relation to medication effect, their distinction remains inconsistent, and the two terms are used interchangeably. Although the potential of pharmacogenomics in psychiatry is apparent and its clinical utility is suboptimal, the uptake of recommendations and guidelines is minimal and research into PGx is not diverse. This article offers an overview of pharmacogenetics (PGx) in psychiatry, explores the difficulties, and provides recommendations on improving its applicability and clinical utility.

Original language	English
Article number	103674
Journal	Asian Journal of Psychiatry
Volume	86
DOIs	https://doi.org/10.1016/j.ajp.2023.103674
Publication status	Published - Aug 2023

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Pharmacogenomics
Precision medicine
Psychiatry PGx

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10.1016/j.ajp.2023.103674

Cite this

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abstract = "Pharmacogenetic studies the influence of inherited characteristics on medication. While different from pharmacogenomics, which is a study of the entire genome in relation to medication effect, their distinction remains inconsistent, and the two terms are used interchangeably. Although the potential of pharmacogenomics in psychiatry is apparent and its clinical utility is suboptimal, the uptake of recommendations and guidelines is minimal and research into PGx is not diverse. This article offers an overview of pharmacogenetics (PGx) in psychiatry, explores the difficulties, and provides recommendations on improving its applicability and clinical utility.",

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T2 - Perspective on clinical utility

AU - Adiukwu, Frances

AU - Adesokun, Olufisayo

AU - Essien, Emmanuel

AU - Yalcin, Nadir

AU - Ransing, Ramdas

AU - Nagendrappa, Sachin

AU - Jatchavala, Chonnakarn

AU - Olakunke, Ayotunde Bolatito

AU - Nawaz, Faisal A.

AU - Khan, Nagina

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Pharmacogenetic testing in psychiatry: Perspective on clinical utility

Abstract

UN SDGs

Keywords

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