TY - JOUR
T1 - Patients with crush syndrome and kidney disease
T2 - lessons learned from the earthquake in Kahramanmaraş, Türkiye
AU - Ozturk, Savas
AU - Tuglular, Serhan
AU - Olmaz, Refik
AU - Kocyigit, Ismail
AU - Kibar, Muge Uzerk
AU - Turgutalp, Kenan
AU - Torun, Dilek
AU - Sahutoglu, Tuncay
AU - Usalan, Ozlem
AU - Gungor, Ozkan
AU - Danis, Ramazan
AU - Yildiz, Gursel
AU - Gurel, Ali
AU - Horoz, Mehmet
AU - Kucuksu, Mehmet
AU - Karakose, Suleyman
AU - Yildirim, Tolga
AU - Altiparmak, Mehmet Riza
AU - Ayli, Mehmet Deniz
AU - Tugcu, Murat
AU - Eren, Zehra
AU - Eroglu, Eray
AU - Yavuz, Yasemin Coskun
AU - Akcali, Esra
AU - Sit, Dede
AU - Polat, Mehmet
AU - Yildirim, Saliha
AU - Alagoz, Selma
AU - Bek, Sibel Gokcay
AU - Pembegul, Irem
AU - Karaaslan, Tahsin
AU - Keles, Mustafa
AU - Sari, Funda
AU - Inci, Ayca
AU - Gorgulu, Numan
AU - Sahin, Gulizar
AU - Aydin, Zeki
AU - Yadigar, Serap
AU - Ulutas, Ozkan
AU - Selcuk, Nedim Yilmaz
AU - Ayar, Yavuz
AU - Bal, Zeynep
AU - Altunok, Murat
AU - Günes Keskin, Ayse Jini
AU - Sipahioglu, Murat Hayri
AU - Ozkutlu, Meliha
AU - Dursun, Belda
AU - Oruc, Aysegul
AU - Hasbal, Nuri Baris
AU - Sevinc, Mustafa
AU - Gul, Semih
AU - Ozturk, Seda Safak
AU - Yildiz, Alaattin
AU - Sever, Mehmet Sukru
N1 - Publisher Copyright:
© 2024 International Society of Nephrology
PY - 2024/11
Y1 - 2024/11
N2 - This study investigated in-hospital outcomes and related factors in patients diagnosed with postearthquake crush syndrome after the earthquakes in Kahramanmaraş, Türkiye. One thousand twenty-four adult patients diagnosed with crush syndrome were analyzed. Data on demographic characteristics, clinical presentation, laboratory values, treatments, and outcomes were collected. A total of 9.8% of patients died during their hospital stay. Nonsurvivors were generally older, more likely to have preexisting chronic kidney disease, and faced more severe injuries and complications, including hypotension-shock, arrhythmias, elevated markers of renal dysfunction, and higher rates of acute kidney injury (AKI) and compartment syndrome. In addition, intensive care unit needs were higher. Multivariate analysis confirmed that age, injury severity, shock, high potassium, uric acid, and lactate levels on admission, development of AKI, compartment syndrome, and intensive care unit admission were significant predictors of mortality. Better disaster preparedness and improved health care infrastructure could be potential explanations for improved in-hospital mortality in the current era, as compared to previous earthquakes.
AB - This study investigated in-hospital outcomes and related factors in patients diagnosed with postearthquake crush syndrome after the earthquakes in Kahramanmaraş, Türkiye. One thousand twenty-four adult patients diagnosed with crush syndrome were analyzed. Data on demographic characteristics, clinical presentation, laboratory values, treatments, and outcomes were collected. A total of 9.8% of patients died during their hospital stay. Nonsurvivors were generally older, more likely to have preexisting chronic kidney disease, and faced more severe injuries and complications, including hypotension-shock, arrhythmias, elevated markers of renal dysfunction, and higher rates of acute kidney injury (AKI) and compartment syndrome. In addition, intensive care unit needs were higher. Multivariate analysis confirmed that age, injury severity, shock, high potassium, uric acid, and lactate levels on admission, development of AKI, compartment syndrome, and intensive care unit admission were significant predictors of mortality. Better disaster preparedness and improved health care infrastructure could be potential explanations for improved in-hospital mortality in the current era, as compared to previous earthquakes.
KW - Türkiye
KW - crush
KW - earthquake
KW - mortality
KW - renal disaster
UR - https://www.scopus.com/pages/publications/85206333232
UR - https://www.webofscience.com/api/gateway?GWVersion=2&SrcApp=performanshacettepe&SrcAuth=WosAPI&KeyUT=WOS:001342504500001&DestLinkType=FullRecord&DestApp=WOS_CPL
U2 - 10.1016/j.kint.2024.08.008
DO - 10.1016/j.kint.2024.08.008
M3 - Article
C2 - 39428169
AN - SCOPUS:85206333232
SN - 0085-2538
VL - 106
SP - 771
EP - 776
JO - Kidney International
JF - Kidney International
IS - 5
ER -