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Non-invasive ventilation in patients with an altered level of consciousness. A clinical review and practical insights

  • Gil Gonçalves
  • , Haitham Saeed
  • , Mohamed E. Abdelrahim
  • , Hadeer S. Harb
  • , Yasmin M. Madney
  • , Kevin Eng
  • , Habib M.R. Karim
  • , Mohamad El-Khatib
  • , Bushra Mina
  • , Szymon Skoczyński
  • , Irena Sarc
  • , Vânia Caldeira
  • , Sara M. Cabral
  • , Bruno Cabrita
  • , Miguel Guia
  • , Jun Duan
  • , Igor Barjaktarevic
  • , Giuseppe Fiorentino
  • , Edoardo Piervincenzi
  • , Güniz Köksal
  • Sibel O. Sarin, Peter J. Papadakos, Benan Bayrakci, Vijay Hadda, Gerhard Laier-Groeneveld, Karen E.A. Burns, Raffaele Scala, Andres C. Alcaraz, Antonio M. Esquinas
  • University of Coimbra
  • Beni-Suef University
  • University of California at Los Angeles
  • All India Institute of Medical Sciences, Raipur
  • American University of Beirut
  • Lenox Hill Hospital
  • Medical University of Silesia in Katowice
  • University Clinic for Pulmonary and Allergic Diseases
  • Hospital de Santa Marta
  • Hospital Pedro Hispano
  • Hospital Professor Doutor Fernando Fonseca
  • First Affiliated Hospital of Chongqing Medical University
  • AO Ospedali dei Colli Monaldi
  • Fondazione Policlinico Universitario A. Gemelli IRCCS-Università Cattolica del Sacro Cuore
  • Istanbul University - Cerrahpaşa
  • Istanbul Umraniye Training and Research Hospital
  • University of Rochester
  • All India Institute of Medical Sciences, New Delhi
  • Schellstrasse
  • University of Toronto
  • IRCCS Policlinico San Donato
  • Hospital Morales Meseguer

Research output: Contribution to journalReview articlepeer-review

8 Citations (Scopus)

Abstract

Non-invasive ventilation has gained an increasingly pivotal role in the treatment of acute hypoxemic and/or hypercapnic respiratory failure and offers multiple advantages over invasive mechanical ventilation. Some of these advantages include the preserva-tion of airway defense mechanisms, a reduced need for sedation, and an avoidance of complications related to endotracheal intubation. Despite its advantages, non-invasive ventilation has some contraindications that include, among them, severe encephalopathy. In this review article, the rationale, evidence, and drawbacks of the use of noninvasive ventilation in the context of hypercapnic and non-hypercapnic patients with an altered level of consciousness are analyzed.

Original languageEnglish
Pages (from-to)233-244
Number of pages12
JournalAdvances in Respiratory Medicine
Volume88
Issue number3
DOIs
Publication statusPublished - 2020

Keywords

  • Altered consciousness
  • Coma
  • Encephalopathy
  • Non-invasive ventilation

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