Investigation of haemolytic and antibacterial activity of calcium phosphate based sealers

  • C. Telli
  • , D. Us
  • , S. Ustacelebi
  • , V. Durmaz

Research output: Contribution to journalArticlepeer-review

Abstract

In the present study, the haemolytic and antibacterial activity of calcium phosphate based sealers named Sankin Apatite type I, II and III were evaluated with respect to other root canal sealers (Express, Endomethasone, Dorifill, CRCS, T. Spad). The haemolytic activity was researched by using human group O erythrocytes and Haemolytic Dose 50 (HD50) titers of each sample was determined. The antibacterial activity on some Gram positive. and negative bacteria was investigated by disc diffusion method by using discs impregnated with the samples. As a result, Sankin Apatite type I, II and III exerted minimal haemolytic activity in low titers and showed no antibacterial effect on the tested bacteria. It is concluded that Sankin Apatite types that have better biologic properties compared with the other root canal sealers can be used practically in dental medicine.

Original languageEnglish
Pages (from-to)66-72
Number of pages7
JournalMikrobiyoloji Bulteni
Volume29
Issue number1
Publication statusPublished - 1995

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

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