Gram-Negative Infections

Matteo Bassetti; Elda Righi; Murat Akova

doi:10.1007/978-3-030-57317-1_12

Gram-Negative Infections

Matteo Bassetti
, Elda Righi
, Murat Akova

Division of Infectious Diseases and Clinical Microbiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter › peer-review

2 Citations (Scopus)

Abstract

During the last 50 years, two major shifts could be noticed in the epidemiology of bacteria causative for infections and particularly bloodstream infections in febrile neutropenic cancer patients. Until the mid-1980s, gram-negative bacteria, particularly Escherichia coli and Pseudomonas aeruginosa, were the main infectious agents in these patients. Then, presumably due to the increased use of high-intensity chemotherapeutic regimens leading to a higher incidence of severe mucositis, the frequent use of fluoroquinolone (FQ) prophylaxis and indwelling long-term vascular catheters, gram positives, particularly coagulase-negative staphylococci and viridans streptococci, became the dominant infecting agents.

Original language	English
Title of host publication	Hematologic Malignancies
Publisher	Springer Science and Business Media Deutschland GmbH
Pages	161-179
Number of pages	19
DOIs	https://doi.org/10.1007/978-3-030-57317-1_12
Publication status	Published - 2021

Publication series

Name	Hematologic Malignancies
ISSN (Print)	2197-9766
ISSN (Electronic)	2197-9774

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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10.1007/978-3-030-57317-1_12

Cite this

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title = "Gram-Negative Infections",

abstract = "During the last 50 years, two major shifts could be noticed in the epidemiology of bacteria causative for infections and particularly bloodstream infections in febrile neutropenic cancer patients. Until the mid-1980s, gram-negative bacteria, particularly Escherichia coli and Pseudomonas aeruginosa, were the main infectious agents in these patients. Then, presumably due to the increased use of high-intensity chemotherapeutic regimens leading to a higher incidence of severe mucositis, the frequent use of fluoroquinolone (FQ) prophylaxis and indwelling long-term vascular catheters, gram positives, particularly coagulase-negative staphylococci and viridans streptococci, became the dominant infecting agents.",

author = "Matteo Bassetti and Elda Righi and Murat Akova",

note = "Publisher Copyright: {\textcopyright} 2020, Springer Nature Switzerland AG.",

year = "2021",

doi = "10.1007/978-3-030-57317-1\_12",

language = "English",

series = "Hematologic Malignancies",

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TY - CHAP

T1 - Gram-Negative Infections

AU - Bassetti, Matteo

AU - Righi, Elda

AU - Akova, Murat

PY - 2021

Y1 - 2021

N2 - During the last 50 years, two major shifts could be noticed in the epidemiology of bacteria causative for infections and particularly bloodstream infections in febrile neutropenic cancer patients. Until the mid-1980s, gram-negative bacteria, particularly Escherichia coli and Pseudomonas aeruginosa, were the main infectious agents in these patients. Then, presumably due to the increased use of high-intensity chemotherapeutic regimens leading to a higher incidence of severe mucositis, the frequent use of fluoroquinolone (FQ) prophylaxis and indwelling long-term vascular catheters, gram positives, particularly coagulase-negative staphylococci and viridans streptococci, became the dominant infecting agents.

AB - During the last 50 years, two major shifts could be noticed in the epidemiology of bacteria causative for infections and particularly bloodstream infections in febrile neutropenic cancer patients. Until the mid-1980s, gram-negative bacteria, particularly Escherichia coli and Pseudomonas aeruginosa, were the main infectious agents in these patients. Then, presumably due to the increased use of high-intensity chemotherapeutic regimens leading to a higher incidence of severe mucositis, the frequent use of fluoroquinolone (FQ) prophylaxis and indwelling long-term vascular catheters, gram positives, particularly coagulase-negative staphylococci and viridans streptococci, became the dominant infecting agents.

UR - https://www.scopus.com/pages/publications/85093918495

U2 - 10.1007/978-3-030-57317-1_12

DO - 10.1007/978-3-030-57317-1_12

M3 - Chapter

AN - SCOPUS:85093918495

T3 - Hematologic Malignancies

SP - 161

EP - 179

BT - Hematologic Malignancies

PB - Springer Science and Business Media Deutschland GmbH

ER -

Gram-Negative Infections

Abstract

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UN SDGs

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