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EUCAST technical note on the EUCAST definitive document EDef 7.2: Method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for yeasts EDef 7.2 (EUCAST-AFST)

  • Maiken C. Arendrup
  • , Manuel Cuenca-Estrella
  • , Cornelia Lass-Flörl
  • , William Hope
  • , M. C. Arendrup
  • , W. W. Hope
  • , C. Flörl
  • , M. Cuenca-Estrella
  • , S. Arikan
  • , F. Barchiesi
  • , J. Bille
  • , E. Chryssanthou
  • , A. Groll
  • , P. Gaustad
  • , H. Järv
  • , N. Klimko
  • , O. Lortholary
  • , T. Matos
  • , C. Moore
  • , A. Schmalreck
  • A. Velegraki, P. Verweij
  • Statens Serum Institut
  • Instituto de Salud Carlos III
  • Innsbruck Medical University
  • University of Manchester

Research output: Contribution to journalArticlepeer-review

368 Citations (Scopus)

Abstract

The European Committee on Antimicrobial Susceptibility Testing-Subcommittee on Antifungal Susceptibility Testing (EUCAST-AFST) has revised the EDef 7.1 document on the method for the determination of broth dilution minimum inhibitory concentrations of antifungal agents for fermentative yeasts. Changes are: dimethylsulphoxide is now the recommended solvent for caspofungin, micafungin and fluconazole; the shelf-life of plates containing the echinocandins prepared from stock solutions in dimethylsulphoxide is extended to 6months at -80°C; testing of amphotericin and Cryptococcus has been incorporated; and minimum inhibitory concentration ranges for quality control strains and anidulafungin are included.

Original languageEnglish
Pages (from-to)E246-E247
JournalClinical Microbiology and Infection
Volume18
Issue number7
DOIs
Publication statusPublished - Jul 2012

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • Antifungals
  • Candida
  • Cryptococcus
  • EUCAST
  • Minimum inhibitory concentration
  • Susceptibility testing
  • Yeast

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