Dynamic light scattering imaging

Dmitry D. Postnov; Jianbo Tang; Sefik Evren Erdener; Kıvılcım Kılıç; David A. Boas

doi:10.1126/SCIADV.ABC4628

Dynamic light scattering imaging

Dmitry D. Postnov
, Jianbo Tang
, Sefik Evren Erdener
, Kıvılcım Kılıç
, David A. Boas

Research output: Contribution to journal › Article › peer-review

128 Citations (Scopus)

Abstract

We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal sampling of speckle fluctuations and a comprehensive model to identify the dynamic scattering regime and obtain a quantitative image of the scatterer dynamics. It reveals errors in the traditional theory of laser Doppler flowmetry and laser speckle contrast imaging and provides guidance on the best model to use in cerebral blood flow imaging.

Original language	English
Article number	eabc4628
Journal	Science Advances
Volume	6
Issue number	45
DOIs	https://doi.org/10.1126/SCIADV.ABC4628
Publication status	Published - 4 Nov 2020
Externally published	Yes

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10.1126/SCIADV.ABC4628

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abstract = "We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal sampling of speckle fluctuations and a comprehensive model to identify the dynamic scattering regime and obtain a quantitative image of the scatterer dynamics. It reveals errors in the traditional theory of laser Doppler flowmetry and laser speckle contrast imaging and provides guidance on the best model to use in cerebral blood flow imaging.",

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AU - Postnov, Dmitry D.

AU - Tang, Jianbo

AU - Erdener, Sefik Evren

AU - Kılıç, Kıvılcım

AU - Boas, David A.

N1 - Publisher Copyright: Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution License 4.0 (CC BY).

PY - 2020/11/4

Y1 - 2020/11/4

N2 - We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal sampling of speckle fluctuations and a comprehensive model to identify the dynamic scattering regime and obtain a quantitative image of the scatterer dynamics. It reveals errors in the traditional theory of laser Doppler flowmetry and laser speckle contrast imaging and provides guidance on the best model to use in cerebral blood flow imaging.

AB - We introduce dynamic light scattering imaging (DLSI) to enable the wide-field measurement of the speckle temporal intensity autocorrelation function. DLSI uses the full temporal sampling of speckle fluctuations and a comprehensive model to identify the dynamic scattering regime and obtain a quantitative image of the scatterer dynamics. It reveals errors in the traditional theory of laser Doppler flowmetry and laser speckle contrast imaging and provides guidance on the best model to use in cerebral blood flow imaging.

UR - https://www.scopus.com/pages/publications/85095800450

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JO - Science Advances

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Dynamic light scattering imaging

Abstract

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