D vitamini metabolik sendrom bileşenlerini etkiler mi?

Metabolic syndrome is a major public health problem which has become increasingly common worlwide with cardiometabolic complications and have high morbidity and mortality. In addition to some genetical features, environmental factors such sedentary lifestyle, improper eating habits constitutes a risk factor for metabolic syndrome. Important components of the metabolic syndrome are dyslipidemia (low HDL levels, high triglycerides level), hyperglycemia, elevated blood pressure and abdominal obesity. Forming metabolic syndrome of other than the five main components, insulin resistance on the basis thought to play a role in several clinical implications of this syndrome is considered. Clinical implications of the metabolic syndrome are; diabetes, essential hypertension, visceral obesity, cardiovascular disorders, insulin resistance, osteoporosis, polycystic ovary syndrome, dyslipidemia, hypercoagulability, hyperuricemia, bone mineral density, fatty liver disease and sleep apnea. In recent years, it is suggested that vitamin D prevents the occurrence of diseases caused by obesity and insulin resistance and the lack of it facilitates occurence of these diseases. Vitamin D deficiency is a public health problem with a growing prevalence in developed and developing countries. Vitamin D is a fat-soluble vitamin, but it is synthesized in the body and affect also other regions it is expressed in the body. Because of this it is described as a hormone in the present day. As well as its known positive effects on calcium balance, it has also physiological functions related the endocrine system. The best indicator showing the level of vitamin D is serum 25 (OH) D level. Vitamin D intake and 25 (OH) D levels are reported to be associated with obesity, metabolic syndrome and diabetes. Diseases which are mostly researched about relation between Vitamin D are cardiovascular disease, kidney disease, diabetes, obesity, metabolic syndrome. In this review, evaluation of the effects of Vitamin D on the metabolic syndrome components of insulin resistance, diabetes, obesity, hypertension, dyslipidemia, cardiovascular disease, fatty liver disease, polycystic ovary syndrome and bone mineral density, was aimed.