Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass

Lea Fayad; Cem Simsek; Dilhana Badurdeen; Christine Hill; Olaya I. Brewer Gutierrez; George Fayad; Margo Dunlap; Anthony N. Kalloo; Mouen A. Khashab; Marcia Canto; Vivek Kumbhari; Arvind J. Trindade; Petros C. Benias; Micheal Raad; Christopher C. Thompson

doi:10.1055/a-1086-3433

Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass

Lea Fayad
, Cem Simsek
, Dilhana Badurdeen
, Christine Hill
, Olaya I. Brewer Gutierrez
, George Fayad
, Margo Dunlap
, Anthony N. Kalloo
, Mouen A. Khashab
, Marcia Canto
, Vivek Kumbhari
, Arvind J. Trindade
, Petros C. Benias
, Micheal Raad
, Christopher C. Thompson

Research output: Contribution to journal › Article › peer-review

14 Citations (Scopus)

Abstract

Background â Cryoballoon ablation could induce stricture formation to achieve outlet and pouch reduction in patients regaining weight after Roux-en-Y gastric bypass (RYGB). This pilot study aimed to assess technical feasibility and short-term efficacy. Methods â A retrospective chart review (JanuaryâŠ-âŠNovember 2018) at two academic centers identified patients with weight regain post-RYGB, treated with cryoablation if pouch >âŠ4âŠcm and/or outlet >âŠ15âŠmm. Patients were scheduled for surveillance endoscopies at 8 weeks. Results â22 patients presented 10.5 years (SD 4.42) post-RYGB with weight regain of 30.9âŠkg (SD 13.7). Technical success was 89.5âŠ% for outlet ablation and 93.0âŠ% for pouch ablation. From baseline to 8 weeks, the outlet was reduced from 24.1âŠmm (95âŠ% confidence interval [CI] 19.8 to 28.5) to 17.1âŠmm (95âŠ%CI 13.1 to 21.1; P âŠ<âŠ0.001), and pouch from 5âŠcm (95âŠ%CI 4.1 to 5.9) to 3.9âŠcm (95âŠ%CI 2.6 to 5.1; P âŠ<âŠ0.05). Total body weight loss at 8 weeks was 8.1âŠ% (SD 12.8âŠ%). Conclusion â Cryoablation appears technically feasible and effective for outlet and/or pouch reduction in the short term.

Original language	English
Pages (from-to)	227-230
Number of pages	4
Journal	Endoscopy
Volume	52
Issue number	3
DOIs	https://doi.org/10.1055/a-1086-3433
Publication status	Published - 1 Mar 2020
Externally published	Yes

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Fayad, L., Simsek, C., Badurdeen, D., Hill, C., Brewer Gutierrez, O. I., Fayad, G., Dunlap, M., Kalloo, A. N., Khashab, M. A., Canto, M., Kumbhari, V., Trindade, A. J., Benias, P. C., Raad, M., & Thompson, C. C. (2020). Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass. Endoscopy, 52(3), 227-230. https://doi.org/10.1055/a-1086-3433

@article{724040bb057a437c930eb351e88bda14,

title = "Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass",

abstract = "Background {\^a} Cryoballoon ablation could induce stricture formation to achieve outlet and pouch reduction in patients regaining weight after Roux-en-Y gastric bypass (RYGB). This pilot study aimed to assess technical feasibility and short-term efficacy. Methods {\^a} A retrospective chart review (January{\^a}{\v S}-{\^a}{\v S}November 2018) at two academic centers identified patients with weight regain post-RYGB, treated with cryoablation if pouch >{\^a}{\v S}4{\^a}{\v S}cm and/or outlet >{\^a}{\v S}15{\^a}{\v S}mm. Patients were scheduled for surveillance endoscopies at 8 weeks. Results {\^a}22 patients presented 10.5 years (SD 4.42) post-RYGB with weight regain of 30.9{\^a}{\v S}kg (SD 13.7). Technical success was 89.5{\^a}{\v S}\% for outlet ablation and 93.0{\^a}{\v S}\% for pouch ablation. From baseline to 8 weeks, the outlet was reduced from 24.1{\^a}{\v S}mm (95{\^a}{\v S}\% confidence interval [CI] 19.8 to 28.5) to 17.1{\^a}{\v S}mm (95{\^a}{\v S}\%CI 13.1 to 21.1; P {\^a}{\v S}<{\^a}{\v S}0.001), and pouch from 5{\^a}{\v S}cm (95{\^a}{\v S}\%CI 4.1 to 5.9) to 3.9{\^a}{\v S}cm (95{\^a}{\v S}\%CI 2.6 to 5.1; P {\^a}{\v S}<{\^a}{\v S}0.05). Total body weight loss at 8 weeks was 8.1{\^a}{\v S}\% (SD 12.8{\^a}{\v S}\%). Conclusion {\^a} Cryoablation appears technically feasible and effective for outlet and/or pouch reduction in the short term.",

author = "Lea Fayad and Cem Simsek and Dilhana Badurdeen and Christine Hill and \{Brewer Gutierrez\}, \{Olaya I.\} and George Fayad and Margo Dunlap and Kalloo, \{Anthony N.\} and Khashab, \{Mouen A.\} and Marcia Canto and Vivek Kumbhari and Trindade, \{Arvind J.\} and Benias, \{Petros C.\} and Micheal Raad and Thompson, \{Christopher C.\}",

year = "2020",

month = mar,

day = "1",

doi = "10.1055/a-1086-3433",

language = "English",

volume = "52",

pages = "227--230",

journal = "Endoscopy",

issn = "0013-726X",

publisher = "Georg Thieme Verlag",

number = "3",

}

Fayad, L, Simsek, C, Badurdeen, D, Hill, C, Brewer Gutierrez, OI, Fayad, G, Dunlap, M, Kalloo, AN, Khashab, MA, Canto, M, Kumbhari, V, Trindade, AJ, Benias, PC, Raad, M & Thompson, CC 2020, 'Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass', Endoscopy, vol. 52, no. 3, pp. 227-230. https://doi.org/10.1055/a-1086-3433

TY - JOUR

T1 - Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass

AU - Fayad, Lea

AU - Simsek, Cem

AU - Badurdeen, Dilhana

AU - Hill, Christine

AU - Brewer Gutierrez, Olaya I.

AU - Fayad, George

AU - Dunlap, Margo

AU - Kalloo, Anthony N.

AU - Khashab, Mouen A.

AU - Canto, Marcia

AU - Kumbhari, Vivek

AU - Trindade, Arvind J.

AU - Benias, Petros C.

AU - Raad, Micheal

AU - Thompson, Christopher C.

PY - 2020/3/1

Y1 - 2020/3/1

N2 - Background â Cryoballoon ablation could induce stricture formation to achieve outlet and pouch reduction in patients regaining weight after Roux-en-Y gastric bypass (RYGB). This pilot study aimed to assess technical feasibility and short-term efficacy. Methods â A retrospective chart review (JanuaryâŠ-âŠNovember 2018) at two academic centers identified patients with weight regain post-RYGB, treated with cryoablation if pouch >âŠ4âŠcm and/or outlet >âŠ15âŠmm. Patients were scheduled for surveillance endoscopies at 8 weeks. Results â22 patients presented 10.5 years (SD 4.42) post-RYGB with weight regain of 30.9âŠkg (SD 13.7). Technical success was 89.5âŠ% for outlet ablation and 93.0âŠ% for pouch ablation. From baseline to 8 weeks, the outlet was reduced from 24.1âŠmm (95âŠ% confidence interval [CI] 19.8 to 28.5) to 17.1âŠmm (95âŠ%CI 13.1 to 21.1; P âŠ<âŠ0.001), and pouch from 5âŠcm (95âŠ%CI 4.1 to 5.9) to 3.9âŠcm (95âŠ%CI 2.6 to 5.1; P âŠ<âŠ0.05). Total body weight loss at 8 weeks was 8.1âŠ% (SD 12.8âŠ%). Conclusion â Cryoablation appears technically feasible and effective for outlet and/or pouch reduction in the short term.

AB - Background â Cryoballoon ablation could induce stricture formation to achieve outlet and pouch reduction in patients regaining weight after Roux-en-Y gastric bypass (RYGB). This pilot study aimed to assess technical feasibility and short-term efficacy. Methods â A retrospective chart review (JanuaryâŠ-âŠNovember 2018) at two academic centers identified patients with weight regain post-RYGB, treated with cryoablation if pouch >âŠ4âŠcm and/or outlet >âŠ15âŠmm. Patients were scheduled for surveillance endoscopies at 8 weeks. Results â22 patients presented 10.5 years (SD 4.42) post-RYGB with weight regain of 30.9âŠkg (SD 13.7). Technical success was 89.5âŠ% for outlet ablation and 93.0âŠ% for pouch ablation. From baseline to 8 weeks, the outlet was reduced from 24.1âŠmm (95âŠ% confidence interval [CI] 19.8 to 28.5) to 17.1âŠmm (95âŠ%CI 13.1 to 21.1; P âŠ<âŠ0.001), and pouch from 5âŠcm (95âŠ%CI 4.1 to 5.9) to 3.9âŠcm (95âŠ%CI 2.6 to 5.1; P âŠ<âŠ0.05). Total body weight loss at 8 weeks was 8.1âŠ% (SD 12.8âŠ%). Conclusion â Cryoablation appears technically feasible and effective for outlet and/or pouch reduction in the short term.

UR - https://www.scopus.com/pages/publications/85080957550

U2 - 10.1055/a-1086-3433

DO - 10.1055/a-1086-3433

M3 - Article

C2 - 31975351

AN - SCOPUS:85080957550

SN - 0013-726X

VL - 52

SP - 227

EP - 230

JO - Endoscopy

JF - Endoscopy

IS - 3

ER -

Cryoballoon ablation for gastric pouch and/or outlet reduction in patients with weight regain post Roux-en-Y gastric bypass

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