Comparison of visual field results of humphrey matrix perimetry and standard automated perimetry with SITA strategy in glaucoma and ocular hypertension subjects

Purpose: To compare the results of Humphrey Matrix 30-2 full threshold test and standard automated perimetry (SAP) using the Swedish Interactive Threshold Algorithm (30-2 SITA standard strategy). Material and Method: Test duration, mean deviation (MD), pattern standard deviation (PSD), number of depressed points on pattern deviation plot (PDP) at level of p<0.05 and p<0.01 were compared using the Wilcoxon signed-rank test. The correlations between MD, PSD and the number of depressed points were analyzed using Spearman's rank correlation coefficient. Kappa (κ) statistic was used to determine the strength of agreement between Matrix and SAP-SITA tests. Results: PSD was higher in Matrix perimetry and the number of depressed points at level of p<0.05 was significantly higher in SAP-SITA test. MD (r=0.48), PSD (r=0.58) and the number of points depressed on PDP at the level of <0.05 and <0.01 (r=0.48 and r=0.47, respectively) showed moderate correlations between the two tests (p<0.001). The agreement between SAP and Matrix perimetry was found to be moderate (κ=0.44, p<0.001). Discussion: Visual field indices and the number of depressed points on PDP of the two perimetries demonstrated only a moderate level of correlation. Therefore, a direct comparison of the global indices or individual test points should be avoided among Matrix perimetry and SAP.