Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741

Evren Hincal; Günsu Soykut; Farouk Tijjani Saad; Seda Vatansever; Isa Abdullahi Baba; İhsan Çalış; Bilgen Kaymakamzade; Eda Becer

doi:10.1007/978-3-030-69292-6_12

Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741

Evren Hincal
, Günsu Soykut
, Farouk Tijjani Saad
, Seda Vatansever
, Isa Abdullahi Baba
, İhsan Çalış
, Bilgen Kaymakamzade
, Eda Becer

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

Mathematical modeling is a key tool in understanding complicated behavior of large signal transduction networks. In this paper a mathematical model is developed to understand the complex signaling behavior of induced apoptosis in Colo-320 and Colo-741 cell lines. The model studies the intrinsic pathway of apoptosis induced by Apaf-1, Cyt-c, and Caspase 3. Experimentally these tests were carried out five times for three groups; namely Control, DCM and Aqueous groups. The main aim is to compare the rate of the occurrence of apoptosis in the two cells Colo-320 and Colo-741 using experimental data. Numerical results reveal that apoptosis takes place at the same time in DCM for Colo-320 and Colo-741, but slightly faster in Aqueous group for Colo-320. It was observed that it took place between the 5–7th h in all the cases.

Original language	English
Title of host publication	Functional Analysis in Interdisciplinary Applications—II - ICAAM, 2018
Editors	Allaberen Ashyralyev, Tynysbek Sh. Kalmenov, Michael V. Ruzhansky, Michael V. Ruzhansky, Makhmud A. Sadybekov, Durvudkhan Suragan
Publisher	Springer
Pages	161-169
Number of pages	9
ISBN (Print)	9783030692919
DOIs	https://doi.org/10.1007/978-3-030-69292-6_12
Publication status	Published - 2021
Externally published	Yes
Event	4th International Conference on Analysis and Applied Mathematics, ICAAM 2018 - Mersin, Turkey Duration: 6 Sept 2018 → 9 Sept 2018

Publication series

Name	Springer Proceedings in Mathematics and Statistics
Volume	351
ISSN (Print)	2194-1009
ISSN (Electronic)	2194-1017

Conference

Conference	4th International Conference on Analysis and Applied Mathematics, ICAAM 2018
Country/Territory	Turkey
City	Mersin
Period	6/09/18 → 9/09/18

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

Keywords

Basic reproduction number
HIV
Mathematical model
Stability analysis

Access to Document

10.1007/978-3-030-69292-6_12

Cite this

Hincal, E., Soykut, G., Tijjani Saad, F., Vatansever, S., Abdullahi Baba, I., Çalış, İ., Kaymakamzade, B., & Becer, E. (2021). Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741. In A. Ashyralyev, T. S. Kalmenov, M. V. Ruzhansky, M. V. Ruzhansky, M. A. Sadybekov, & D. Suragan (Eds.), Functional Analysis in Interdisciplinary Applications—II - ICAAM, 2018 (pp. 161-169). (Springer Proceedings in Mathematics and Statistics; Vol. 351). Springer. https://doi.org/10.1007/978-3-030-69292-6_12

Hincal, Evren ; Soykut, Günsu ; Tijjani Saad, Farouk et al. / Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741. Functional Analysis in Interdisciplinary Applications—II - ICAAM, 2018. editor / Allaberen Ashyralyev ; Tynysbek Sh. Kalmenov ; Michael V. Ruzhansky ; Michael V. Ruzhansky ; Makhmud A. Sadybekov ; Durvudkhan Suragan. Springer, 2021. pp. 161-169 (Springer Proceedings in Mathematics and Statistics).

@inproceedings{d22e2f41825b4bb583880128dbe32910,

title = "Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741",

abstract = "Mathematical modeling is a key tool in understanding complicated behavior of large signal transduction networks. In this paper a mathematical model is developed to understand the complex signaling behavior of induced apoptosis in Colo-320 and Colo-741 cell lines. The model studies the intrinsic pathway of apoptosis induced by Apaf-1, Cyt-c, and Caspase 3. Experimentally these tests were carried out five times for three groups; namely Control, DCM and Aqueous groups. The main aim is to compare the rate of the occurrence of apoptosis in the two cells Colo-320 and Colo-741 using experimental data. Numerical results reveal that apoptosis takes place at the same time in DCM for Colo-320 and Colo-741, but slightly faster in Aqueous group for Colo-320. It was observed that it took place between the 5–7th h in all the cases.",

keywords = "Basic reproduction number, HIV, Mathematical model, Stability analysis",

author = "Evren Hincal and G{\"u}nsu Soykut and \{Tijjani Saad\}, Farouk and Seda Vatansever and \{Abdullahi Baba\}, Isa and İhsan {\c C}alı{\c s} and Bilgen Kaymakamzade and Eda Becer",

note = "Publisher Copyright: {\textcopyright} 2021, Springer Nature Switzerland AG.; 4th International Conference on Analysis and Applied Mathematics, ICAAM 2018 ; Conference date: 06-09-2018 Through 09-09-2018",

year = "2021",

doi = "10.1007/978-3-030-69292-6\_12",

language = "English",

isbn = "9783030692919",

series = "Springer Proceedings in Mathematics and Statistics",

publisher = "Springer",

pages = "161--169",

editor = "Allaberen Ashyralyev and Kalmenov, \{Tynysbek Sh.\} and Ruzhansky, \{Michael V.\} and Ruzhansky, \{Michael V.\} and Sadybekov, \{Makhmud A.\} and Durvudkhan Suragan",

booktitle = "Functional Analysis in Interdisciplinary Applications—II - ICAAM, 2018",

address = "Germany",

}

Hincal, E, Soykut, G, Tijjani Saad, F, Vatansever, S, Abdullahi Baba, I, Çalış, İ, Kaymakamzade, B & Becer, E 2021, Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741. in A Ashyralyev, TS Kalmenov, MV Ruzhansky, MV Ruzhansky, MA Sadybekov & D Suragan (eds), Functional Analysis in Interdisciplinary Applications—II - ICAAM, 2018. Springer Proceedings in Mathematics and Statistics, vol. 351, Springer, pp. 161-169, 4th International Conference on Analysis and Applied Mathematics, ICAAM 2018, Mersin, Turkey, 6/09/18. https://doi.org/10.1007/978-3-030-69292-6_12

Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741. / Hincal, Evren; Soykut, Günsu; Tijjani Saad, Farouk et al.
Functional Analysis in Interdisciplinary Applications—II - ICAAM, 2018. ed. / Allaberen Ashyralyev; Tynysbek Sh. Kalmenov; Michael V. Ruzhansky; Michael V. Ruzhansky; Makhmud A. Sadybekov; Durvudkhan Suragan. Springer, 2021. p. 161-169 (Springer Proceedings in Mathematics and Statistics; Vol. 351).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

TY - GEN

T1 - Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741

AU - Hincal, Evren

AU - Soykut, Günsu

AU - Tijjani Saad, Farouk

AU - Vatansever, Seda

AU - Abdullahi Baba, Isa

AU - Çalış, İhsan

AU - Kaymakamzade, Bilgen

AU - Becer, Eda

PY - 2021

Y1 - 2021

N2 - Mathematical modeling is a key tool in understanding complicated behavior of large signal transduction networks. In this paper a mathematical model is developed to understand the complex signaling behavior of induced apoptosis in Colo-320 and Colo-741 cell lines. The model studies the intrinsic pathway of apoptosis induced by Apaf-1, Cyt-c, and Caspase 3. Experimentally these tests were carried out five times for three groups; namely Control, DCM and Aqueous groups. The main aim is to compare the rate of the occurrence of apoptosis in the two cells Colo-320 and Colo-741 using experimental data. Numerical results reveal that apoptosis takes place at the same time in DCM for Colo-320 and Colo-741, but slightly faster in Aqueous group for Colo-320. It was observed that it took place between the 5–7th h in all the cases.

AB - Mathematical modeling is a key tool in understanding complicated behavior of large signal transduction networks. In this paper a mathematical model is developed to understand the complex signaling behavior of induced apoptosis in Colo-320 and Colo-741 cell lines. The model studies the intrinsic pathway of apoptosis induced by Apaf-1, Cyt-c, and Caspase 3. Experimentally these tests were carried out five times for three groups; namely Control, DCM and Aqueous groups. The main aim is to compare the rate of the occurrence of apoptosis in the two cells Colo-320 and Colo-741 using experimental data. Numerical results reveal that apoptosis takes place at the same time in DCM for Colo-320 and Colo-741, but slightly faster in Aqueous group for Colo-320. It was observed that it took place between the 5–7th h in all the cases.

KW - Basic reproduction number

KW - HIV

KW - Mathematical model

KW - Stability analysis

UR - https://www.scopus.com/pages/publications/85112223355

U2 - 10.1007/978-3-030-69292-6_12

DO - 10.1007/978-3-030-69292-6_12

M3 - Conference contribution

AN - SCOPUS:85112223355

SN - 9783030692919

T3 - Springer Proceedings in Mathematics and Statistics

SP - 161

EP - 169

BT - Functional Analysis in Interdisciplinary Applications—II - ICAAM, 2018

A2 - Ashyralyev, Allaberen

A2 - Kalmenov, Tynysbek Sh.

A2 - Ruzhansky, Michael V.

A2 - Sadybekov, Makhmud A.

A2 - Suragan, Durvudkhan

PB - Springer

T2 - 4th International Conference on Analysis and Applied Mathematics, ICAAM 2018

Y2 - 6 September 2018 through 9 September 2018

ER -

Hincal E, Soykut G, Tijjani Saad F, Vatansever S, Abdullahi Baba I, Çalış İ et al. Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741. In Ashyralyev A, Kalmenov TS, Ruzhansky MV, Ruzhansky MV, Sadybekov MA, Suragan D, editors, Functional Analysis in Interdisciplinary Applications—II - ICAAM, 2018. Springer. 2021. p. 161-169. (Springer Proceedings in Mathematics and Statistics). doi: 10.1007/978-3-030-69292-6_12

Comparison of the Rate of Induced Intrinsic Pathway of Apoptosis on COLO-320 and COLO-741

Abstract

Publication series

Conference

UN SDGs

Keywords

Access to Document

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