Cleaning and coating procedures determine biological properties of gyroid porous titanium implants

Fatma Nur Depboylu; Beliz Taşkonak; Petek Korkusuz; Evren Yasa; Olatunji Ajiteru; Kyu Young Choi; Chan Hum Park; Özgür Poyraz; Andrei Alexandru Popa; Feza Korkusuz

doi:10.1007/s42247-024-00774-2

Cleaning and coating procedures determine biological properties of gyroid porous titanium implants

Fatma Nur Depboylu
, Beliz Taşkonak
, Petek Korkusuz
, Evren Yasa
, Olatunji Ajiteru
, Kyu Young Choi
, Chan Hum Park
, Özgür Poyraz
, Andrei Alexandru Popa
, Feza Korkusuz

Research output: Contribution to journal › Article › peer-review

2 Citations (Scopus)

Abstract

Cleaning and coating processes as well as biocompatibility of gyroid commercially pure titanium (Cp-Ti) biomedical implants using the laser powder bed fusion (L-PBF) technology were analyzed. Etching time for cleaning of gyroid Cp-Ti biomedical implants were determined to remove non-melted particles from the surface. Nano hydroxyapatite (nHA) and polylactic acid (PLA) composite coating on the gyroid Cp-Ti implants via dip coating were optimized. Dip coating’s withdrawal speed also, the amount of nHA:PLA and viscosity effects of composite were evaluated. 1000 mm/min withdrawal speed prevented clogging of the pores. In addition, silk fibroin was coated on gyroid Cp-Ti implants with electro deposition method. Optimum coating thicknesses were achieved. Biocompatibility after PLA:nHA and silk fibroin were studied. Gyroid and solid Cp-Ti presented 3% and 1% mass loss after a minute of HF/HNO₃ etching. The three-minute etching protocol led to the highest micro pit width formation on the surfaces. 70:30 PLA:nHA and silk fibroin established crack-free coatings on gyroid Cp-Ti surfaces. MTT, live-dead cell assay revealed good biocompatibility after coating.

Original language	English
Article number	125217
Pages (from-to)	2711-2729
Number of pages	19
Journal	Emergent Materials
Volume	7
Issue number	6
DOIs	https://doi.org/10.1007/s42247-024-00774-2
Publication status	Published - Dec 2024

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 7 Affordable and Clean Energy

Keywords

Cell viability
Chemical etching
Composite
Dip coating
Electro-deposition technique
Silk-fibroin

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10.1007/s42247-024-00774-2

Cite this

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title = "Cleaning and coating procedures determine biological properties of gyroid porous titanium implants",

abstract = "Cleaning and coating processes as well as biocompatibility of gyroid commercially pure titanium (Cp-Ti) biomedical implants using the laser powder bed fusion (L-PBF) technology were analyzed. Etching time for cleaning of gyroid Cp-Ti biomedical implants were determined to remove non-melted particles from the surface. Nano hydroxyapatite (nHA) and polylactic acid (PLA) composite coating on the gyroid Cp-Ti implants via dip coating were optimized. Dip coating{\textquoteright}s withdrawal speed also, the amount of nHA:PLA and viscosity effects of composite were evaluated. 1000 mm/min withdrawal speed prevented clogging of the pores. In addition, silk fibroin was coated on gyroid Cp-Ti implants with electro deposition method. Optimum coating thicknesses were achieved. Biocompatibility after PLA:nHA and silk fibroin were studied. Gyroid and solid Cp-Ti presented 3\% and 1\% mass loss after a minute of HF/HNO3 etching. The three-minute etching protocol led to the highest micro pit width formation on the surfaces. 70:30 PLA:nHA and silk fibroin established crack-free coatings on gyroid Cp-Ti surfaces. MTT, live-dead cell assay revealed good biocompatibility after coating.",

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AU - Depboylu, Fatma Nur

AU - Taşkonak, Beliz

AU - Korkusuz, Petek

AU - Yasa, Evren

AU - Ajiteru, Olatunji

AU - Choi, Kyu Young

AU - Park, Chan Hum

AU - Poyraz, Özgür

AU - Popa, Andrei Alexandru

AU - Korkusuz, Feza

N1 - Publisher Copyright: © The Author(s) 2024.

PY - 2024/12

Y1 - 2024/12

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AB - Cleaning and coating processes as well as biocompatibility of gyroid commercially pure titanium (Cp-Ti) biomedical implants using the laser powder bed fusion (L-PBF) technology were analyzed. Etching time for cleaning of gyroid Cp-Ti biomedical implants were determined to remove non-melted particles from the surface. Nano hydroxyapatite (nHA) and polylactic acid (PLA) composite coating on the gyroid Cp-Ti implants via dip coating were optimized. Dip coating’s withdrawal speed also, the amount of nHA:PLA and viscosity effects of composite were evaluated. 1000 mm/min withdrawal speed prevented clogging of the pores. In addition, silk fibroin was coated on gyroid Cp-Ti implants with electro deposition method. Optimum coating thicknesses were achieved. Biocompatibility after PLA:nHA and silk fibroin were studied. Gyroid and solid Cp-Ti presented 3% and 1% mass loss after a minute of HF/HNO3 etching. The three-minute etching protocol led to the highest micro pit width formation on the surfaces. 70:30 PLA:nHA and silk fibroin established crack-free coatings on gyroid Cp-Ti surfaces. MTT, live-dead cell assay revealed good biocompatibility after coating.

KW - Cell viability

KW - Chemical etching

KW - Composite

KW - Dip coating

KW - Electro-deposition technique

KW - Silk-fibroin

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ER -

Cleaning and coating procedures determine biological properties of gyroid porous titanium implants

Abstract

UN SDGs

Keywords

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