Children with lymphoma presenting with hemophagocytic lymphohistiocytosis

Tekin Aksu; Turan Bayhan; Belgin Gülhan; Selma Çakmakcı; Ayşe Selcen Oğuz; Neşe Yaralı; Namık Yaşar Özbek; İnci İlhan

doi:10.24953/turkjped.2020.02.016

Children with lymphoma presenting with hemophagocytic lymphohistiocytosis

Tekin Aksu
, Turan Bayhan
, Belgin Gülhan
, Selma Çakmakcı
, Ayşe Selcen Oğuz
, Neşe Yaralı
, Namık Yaşar Özbek
, İnci İlhan

University of Health Sciences

Research output: Contribution to journal › Article › peer-review

3 Citations (Scopus)

Abstract

BACKGROUND: < 7b > Hemophagocytic lymphohistiocytosis (HLH) may precede malignancy, in particular lymphomas and leukemias. However, the causative factors, appropriate treatment and the prognosis of this association is not established. CASE: Herein, we present two patients, one with nodular sclerosing Hodgkin lymphoma (HL) and concomitant Epstein-Barr virus (EBV) infection, and the other with anaplastic large cell lymphoma (ALCL), presented as malignancy associated HLH. CONCLUSION: In our patients, malignancy directed therapy was sufficient to treat HLH symptoms both at presentation and at recurrence in the second patient.

Original language	English
Pages (from-to)	284-288
Number of pages	5
Journal	Turkish Journal of Pediatrics
Volume	62
Issue number	2
DOIs	https://doi.org/10.24953/turkjped.2020.02.016
Publication status	Published - 2020
Externally published	Yes

Keywords

Hodgkin lymphoma
anaplastic large cell lymphoma
hemophagocytic lymphohistiocytosis

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10.24953/turkjped.2020.02.016

Cite this

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title = "Children with lymphoma presenting with hemophagocytic lymphohistiocytosis",

abstract = "BACKGROUND: < 7b > Hemophagocytic lymphohistiocytosis (HLH) may precede malignancy, in particular lymphomas and leukemias. However, the causative factors, appropriate treatment and the prognosis of this association is not established. CASE: Herein, we present two patients, one with nodular sclerosing Hodgkin lymphoma (HL) and concomitant Epstein-Barr virus (EBV) infection, and the other with anaplastic large cell lymphoma (ALCL), presented as malignancy associated HLH. CONCLUSION: In our patients, malignancy directed therapy was sufficient to treat HLH symptoms both at presentation and at recurrence in the second patient.",

keywords = "Hodgkin lymphoma, anaplastic large cell lymphoma, hemophagocytic lymphohistiocytosis",

author = "Tekin Aksu and Turan Bayhan and Belgin G{\"u}lhan and Selma {\c C}akmakcı and Oğuz, \{Ay{\c s}e Selcen\} and Ne{\c s}e Yaralı and {\"O}zbek, \{Namık Ya{\c s}ar\} and İnci İlhan",

year = "2020",

doi = "10.24953/turkjped.2020.02.016",

language = "English",

volume = "62",

pages = "284--288",

journal = "Turkish Journal of Pediatrics",

issn = "0041-4301",

publisher = "Turkish National Pediatric Society",

number = "2",

}

TY - JOUR

T1 - Children with lymphoma presenting with hemophagocytic lymphohistiocytosis

AU - Aksu, Tekin

AU - Bayhan, Turan

AU - Gülhan, Belgin

AU - Çakmakcı, Selma

AU - Oğuz, Ayşe Selcen

AU - Yaralı, Neşe

AU - Özbek, Namık Yaşar

AU - İlhan, İnci

PY - 2020

Y1 - 2020

N2 - BACKGROUND: < 7b > Hemophagocytic lymphohistiocytosis (HLH) may precede malignancy, in particular lymphomas and leukemias. However, the causative factors, appropriate treatment and the prognosis of this association is not established. CASE: Herein, we present two patients, one with nodular sclerosing Hodgkin lymphoma (HL) and concomitant Epstein-Barr virus (EBV) infection, and the other with anaplastic large cell lymphoma (ALCL), presented as malignancy associated HLH. CONCLUSION: In our patients, malignancy directed therapy was sufficient to treat HLH symptoms both at presentation and at recurrence in the second patient.

AB - BACKGROUND: < 7b > Hemophagocytic lymphohistiocytosis (HLH) may precede malignancy, in particular lymphomas and leukemias. However, the causative factors, appropriate treatment and the prognosis of this association is not established. CASE: Herein, we present two patients, one with nodular sclerosing Hodgkin lymphoma (HL) and concomitant Epstein-Barr virus (EBV) infection, and the other with anaplastic large cell lymphoma (ALCL), presented as malignancy associated HLH. CONCLUSION: In our patients, malignancy directed therapy was sufficient to treat HLH symptoms both at presentation and at recurrence in the second patient.

KW - Hodgkin lymphoma

KW - anaplastic large cell lymphoma

KW - hemophagocytic lymphohistiocytosis

UR - https://www.scopus.com/pages/publications/85084882228

U2 - 10.24953/turkjped.2020.02.016

DO - 10.24953/turkjped.2020.02.016

M3 - Article

C2 - 32419422

AN - SCOPUS:85084882228

SN - 0041-4301

VL - 62

SP - 284

EP - 288

JO - Turkish Journal of Pediatrics

JF - Turkish Journal of Pediatrics

IS - 2

ER -

Children with lymphoma presenting with hemophagocytic lymphohistiocytosis

Abstract

Keywords

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