Abstract
Cancer stem cells represent a rare subpopulation of cancer cells carrying self-renewal and differentiation features in multi-step tumorigenesis, tumor recurrence and metastasis. Pro-inflammatory stress is highly associated with cancer stemness via induction of cytokines, tumor-promoting immune cells and cancer stemness-related signaling pathways. This review summarizes the major pro-inflammatory factors affecting cancer stem cell characteristics and the critical immuno-therapeutic strategies to eliminate cancer stem cells.
| Original language | English |
|---|---|
| Pages (from-to) | 792-800 |
| Number of pages | 9 |
| Journal | Current Stem Cell Research and Therapy |
| Volume | 16 |
| Issue number | 7 |
| DOIs | |
| Publication status | Published - Oct 2021 |
UN SDGs
This output contributes to the following UN Sustainable Development Goals (SDGs)
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SDG 3 Good Health and Well-being
Keywords
- Cancer stem cells
- Cancer stemness
- Immuno-therapeutic strategies
- Inflammation
- Pro-inflammatory cytokines
- Pro-inflammatory stress
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