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Aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications

  • Tao Chen
  • , Mohammed Ibrahim Shukoor
  • , Yan Chen
  • , Quan Yuan
  • , Zhi Zhu
  • , Zilong Zhao
  • , Basri Gulbakan
  • , Weihong Tan

Research output: Contribution to journalReview articlepeer-review

118 Citations (Scopus)

Abstract

In recent years, nanomaterials have captured the attention of scientists from a wide spectrum of domains. With their unique properties, nanomaterials offer great promise for numerous applications, ranging from catalysis to energy harvesting and information technology. Functionalized with the desired biomolecules, nanomaterials can also be utilized for many biomedical applications. This paper summarizes recent achievements in the use of aptamer-conjugated nanomaterials for bioanalysis and biotechnology applications. First, we discuss the features and properties of aptamers and then illustrate the use of aptamer-conjugated nanomaterials as sensing platforms and delivery vehicles, emphasizing how such integration can result in enhanced sensitivity and selectivity.

Original languageEnglish
Pages (from-to)546-556
Number of pages11
JournalNanoscale
Volume3
Issue number2
DOIs
Publication statusPublished - Feb 2011
Externally publishedYes

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