An overview: Radiotracers and nano-radiopharmaceuticals for diagnosis of Parkinson's disease

Nur Ozolmez; Mine Silindir-Gunay; Bilge Volkan-Salanci

doi:10.1016/j.apradiso.2023.111110

An overview: Radiotracers and nano-radiopharmaceuticals for diagnosis of Parkinson's disease

Research output: Contribution to journal › Review article › peer-review

6 Citations (Scopus)

Abstract

Parkinson's disease (PD) is a widespread progressive neurodegenerative disease. Clinical diagnosis approaches are insufficient to provide an early and accurate diagnosis before a substantial of loss of dopaminergic neurons. PET and SPECT can be used for accurate and early diagnosis of PD by using target-specific radiotracers. Additionally, the importance of BBB penetrating targeted nanosystems has increased in recent years. This article reviews targeted radiopharmaceuticals used in clinics and novel nanocarriers for research purposes of PD imaging.

Original language	English
Article number	111110
Journal	Applied Radiation and Isotopes
Volume	203
DOIs	https://doi.org/10.1016/j.apradiso.2023.111110
Publication status	Published - Jan 2024

Keywords

Nuclear imaging
PET
Parkinson's disease
Radiolabeled nanocarriers
Radiopharmaceuticals
SPECT

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10.1016/j.apradiso.2023.111110

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title = "An overview: Radiotracers and nano-radiopharmaceuticals for diagnosis of Parkinson's disease",

abstract = "Parkinson's disease (PD) is a widespread progressive neurodegenerative disease. Clinical diagnosis approaches are insufficient to provide an early and accurate diagnosis before a substantial of loss of dopaminergic neurons. PET and SPECT can be used for accurate and early diagnosis of PD by using target-specific radiotracers. Additionally, the importance of BBB penetrating targeted nanosystems has increased in recent years. This article reviews targeted radiopharmaceuticals used in clinics and novel nanocarriers for research purposes of PD imaging.",

keywords = "Nuclear imaging, PET, Parkinson's disease, Radiolabeled nanocarriers, Radiopharmaceuticals, SPECT",

author = "Nur Ozolmez and Mine Silindir-Gunay and Bilge Volkan-Salanci",

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T2 - Radiotracers and nano-radiopharmaceuticals for diagnosis of Parkinson's disease

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AU - Silindir-Gunay, Mine

AU - Volkan-Salanci, Bilge

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Y1 - 2024/1

N2 - Parkinson's disease (PD) is a widespread progressive neurodegenerative disease. Clinical diagnosis approaches are insufficient to provide an early and accurate diagnosis before a substantial of loss of dopaminergic neurons. PET and SPECT can be used for accurate and early diagnosis of PD by using target-specific radiotracers. Additionally, the importance of BBB penetrating targeted nanosystems has increased in recent years. This article reviews targeted radiopharmaceuticals used in clinics and novel nanocarriers for research purposes of PD imaging.

AB - Parkinson's disease (PD) is a widespread progressive neurodegenerative disease. Clinical diagnosis approaches are insufficient to provide an early and accurate diagnosis before a substantial of loss of dopaminergic neurons. PET and SPECT can be used for accurate and early diagnosis of PD by using target-specific radiotracers. Additionally, the importance of BBB penetrating targeted nanosystems has increased in recent years. This article reviews targeted radiopharmaceuticals used in clinics and novel nanocarriers for research purposes of PD imaging.

KW - Nuclear imaging

KW - PET

KW - Parkinson's disease

KW - Radiolabeled nanocarriers

KW - Radiopharmaceuticals

KW - SPECT

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DO - 10.1016/j.apradiso.2023.111110

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AN - SCOPUS:85177978009

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JO - Applied Radiation and Isotopes

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ER -

An overview: Radiotracers and nano-radiopharmaceuticals for diagnosis of Parkinson's disease

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Keywords

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