Amylase/creatinine clearance ratio in diabetic ketoacidosis: A case report

  • Özlem Boybeyi
  • , Ayça Törel Ergür
  • , Zarife Esra Dursun
  • , Fulya Gülerman

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

Diabetic ketoacidosis (DKA) accompanies any other intra-abdominal pathology. Serum amylase/lipase levels are commonly used in order to rule out acute pancreatitis in patients having abdominal pain in DKA. A more specific and noninvasive diagnostic tool - amylase/creatinine clearance ratio (ACCR) - can be used to rule out pancreatitis in patients with DKA. A 14-year-old girl was admitted with abdominal pain and nausea. She had been followed up for type 1 diabetes mellitus for the last 5 years. The serum amylase levels were increased up to 687 U/L (normal: 28-120 U/L) on the third day of hospitalization. Simultaneous serum and urinary amylase concentrations were measured, and ACCR was calculated (1.2%). The diagnosis of pancreatitis was ruled out. The serum amylase levels decreased in the following days, and she was discharged. ACCR determination is a simple and specific test to diagnose pancreatitis, especially in patients with DKA.

Original languageEnglish
Pages (from-to)1243-1245
Number of pages3
JournalJournal of Pediatric Endocrinology and Metabolism
Volume27
Issue number11-12
DOIs
Publication statusPublished - 1 Nov 2014
Externally publishedYes

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

  1. SDG 3 - Good Health and Well-being
    SDG 3 Good Health and Well-being

Keywords

  • amylase/creatinine clearance ratio
  • diabetic ketoacidosis
  • pancreatitis

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