Alkaloids of Galanthus-elwesii

A LATVALA; MA ONUR; T GOZLER; A LINDEN; B KIVCAK; M HESSE

doi:10.1016/0031-9422(95)00187-C

Alkaloids of Galanthus-elwesii

A LATVALA
, MA ONUR
, T GOZLER
, A LINDEN
, B KIVCAK
, M HESSE

Division of General Biology

Research output: Contribution to journal › Article › peer-review

Abstract

Six new lycorenine-type alkaloids, (+)-5-methoxy-9-0-demethylhomolycorine, (+)-galwesine, (+)-9-0-demethylgalwesine, (+)-16-hydroxygalwesine, (+)-16-hydroxy-9-0-demethylgalwesine and galasine, were isolated from whole plants of Galanthus elwesii. Additionally, 12 known alkaloids, (-)-galanthamine, (-)-sanguinine, (-)-leucotamine, (-)-0-methylleucotamine, (+/-)-narwedine, (-)-N-demethylgalanthamine, (+)-11-hydroxyvittatine, (+)-9-0-demethylhomolycorine, (-)-lycorine, (-)-galanthine, hordenine, and (E)-N-feruloyltyramine were also obtained. Of these alkaloids, only galanthamine and lycorine have been isolated previously from G. elwesii. Identification and structural elucidation were achieved using spectrometric techniques.

Original language	English
Pages (from-to)	1229-1240
Number of pages	12
Journal	Phytochemistry
Volume	39
Issue number	5
DOIs	https://doi.org/10.1016/0031-9422(95)00187-C
Publication status	Published - Jul 1995

Keywords

16-hydroxy-9-o-demethylgalwesine
16-hydroxygalwesine
5-methoxy-9-o-demethylhomolycorine
9-o-demethylgalwesine
9-o-demethylhomolycorine
Amaryllidaceae
Galanthus elwesii
Galasine
Galwesine
Leucotamine
O-methyl-leucotamine

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10.1016/0031-9422(95)00187-C

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title = "Alkaloids of Galanthus-elwesii",

abstract = "Six new lycorenine-type alkaloids, (+)-5-methoxy-9-0-demethylhomolycorine, (+)-galwesine, (+)-9-0-demethylgalwesine, (+)-16-hydroxygalwesine, (+)-16-hydroxy-9-0-demethylgalwesine and galasine, were isolated from whole plants of Galanthus elwesii. Additionally, 12 known alkaloids, (-)-galanthamine, (-)-sanguinine, (-)-leucotamine, (-)-0-methylleucotamine, (+/-)-narwedine, (-)-N-demethylgalanthamine, (+)-11-hydroxyvittatine, (+)-9-0-demethylhomolycorine, (-)-lycorine, (-)-galanthine, hordenine, and (E)-N-feruloyltyramine were also obtained. Of these alkaloids, only galanthamine and lycorine have been isolated previously from G. elwesii. Identification and structural elucidation were achieved using spectrometric techniques.",

keywords = "16-hydroxy-9-o-demethylgalwesine, 16-hydroxygalwesine, 5-methoxy-9-o-demethylhomolycorine, 9-o-demethylgalwesine, 9-o-demethylhomolycorine, Amaryllidaceae, Galanthus elwesii, Galasine, Galwesine, Leucotamine, O-methyl-leucotamine",

author = "A LATVALA and MA ONUR and T GOZLER and A LINDEN and B KIVCAK and M HESSE",

year = "1995",

month = jul,

doi = "10.1016/0031-9422(95)00187-C",

language = "English",

volume = "39",

pages = "1229--1240",

journal = "Phytochemistry",

issn = "0031-9422",

publisher = "Elsevier Ltd",

number = "5",

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TY - JOUR

T1 - Alkaloids of Galanthus-elwesii

AU - LATVALA, A

AU - ONUR, MA

AU - GOZLER, T

AU - LINDEN, A

AU - KIVCAK, B

AU - HESSE, M

PY - 1995/7

Y1 - 1995/7

N2 - Six new lycorenine-type alkaloids, (+)-5-methoxy-9-0-demethylhomolycorine, (+)-galwesine, (+)-9-0-demethylgalwesine, (+)-16-hydroxygalwesine, (+)-16-hydroxy-9-0-demethylgalwesine and galasine, were isolated from whole plants of Galanthus elwesii. Additionally, 12 known alkaloids, (-)-galanthamine, (-)-sanguinine, (-)-leucotamine, (-)-0-methylleucotamine, (+/-)-narwedine, (-)-N-demethylgalanthamine, (+)-11-hydroxyvittatine, (+)-9-0-demethylhomolycorine, (-)-lycorine, (-)-galanthine, hordenine, and (E)-N-feruloyltyramine were also obtained. Of these alkaloids, only galanthamine and lycorine have been isolated previously from G. elwesii. Identification and structural elucidation were achieved using spectrometric techniques.

AB - Six new lycorenine-type alkaloids, (+)-5-methoxy-9-0-demethylhomolycorine, (+)-galwesine, (+)-9-0-demethylgalwesine, (+)-16-hydroxygalwesine, (+)-16-hydroxy-9-0-demethylgalwesine and galasine, were isolated from whole plants of Galanthus elwesii. Additionally, 12 known alkaloids, (-)-galanthamine, (-)-sanguinine, (-)-leucotamine, (-)-0-methylleucotamine, (+/-)-narwedine, (-)-N-demethylgalanthamine, (+)-11-hydroxyvittatine, (+)-9-0-demethylhomolycorine, (-)-lycorine, (-)-galanthine, hordenine, and (E)-N-feruloyltyramine were also obtained. Of these alkaloids, only galanthamine and lycorine have been isolated previously from G. elwesii. Identification and structural elucidation were achieved using spectrometric techniques.

KW - 16-hydroxy-9-o-demethylgalwesine

KW - 16-hydroxygalwesine

KW - 5-methoxy-9-o-demethylhomolycorine

KW - 9-o-demethylgalwesine

KW - 9-o-demethylhomolycorine

KW - Amaryllidaceae

KW - Galanthus elwesii

KW - Galasine

KW - Galwesine

KW - Leucotamine

KW - O-methyl-leucotamine

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U2 - 10.1016/0031-9422(95)00187-C

DO - 10.1016/0031-9422(95)00187-C

M3 - Article

SN - 0031-9422

VL - 39

SP - 1229

EP - 1240

JO - Phytochemistry

JF - Phytochemistry

IS - 5

ER -

Alkaloids of Galanthus-elwesii

Abstract

Keywords

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