A constrained, force-directed layout algorithm for biological pathways

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12 Citations (Scopus)

Abstract

We present a new elegant algorithm for layout of biological signaling pathways. It uses a force-directed layout scheme, taking into account directional and regional constraints enforced by different molecular interaction types and subcellular locations in a cell. The algorithm has been successfully implemented as part of a pathway integration and analysis toolkit named Patika, and results with respect to computational complexity and quality of the layout have been found satisfactory.

Original languageEnglish
Title of host publicationLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
EditorsGiuseppe Liotta
PublisherSpringer Verlag
Pages314-319
Number of pages6
ISBN (Print)3540208313, 9783540208310
DOIs
Publication statusPublished - 2004
Externally publishedYes
Event11th International Symposium on Graph Drawing, GD 2003 - Perugia, Italy
Duration: 21 Sept 200324 Sept 2003

Publication series

NameLecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
Volume2912
ISSN (Print)0302-9743
ISSN (Electronic)1611-3349

Conference

Conference11th International Symposium on Graph Drawing, GD 2003
Country/TerritoryItaly
CityPerugia
Period21/09/0324/09/03

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